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Welcome to the official database of the IUPHAR Committee on Receptor Nomenclature and Drug Classification.

Incorporating the IUPHAR Database of G Protein-Coupled Receptors and the IUPHAR Database of Voltage-Gated and Ligand-Gated Ion Channels.

Recent updates include:

• New ion channel data released
  
  • Detailed pharmacological and functional annotation added to the database for 7 voltage-gated and 3 ligand-gated ion channel families:

  VGIC families	LGIC families
  Calcium-activated potassium channels CatSper and two-pore channels Cyclic nucleotide-regulated channels Inwardly rectifying potassium channels Voltage-gated calcium channels Voltage-gated potassium channels Voltage-gated sodium channels	5-HT3 receptors Glycine receptors Zinc-activated channel

• 3 GPCR families updated
  • Detailed annotation and an introduction have been added for the Melanin-concentrating hormone receptor family.
  • The P2Y receptor family data and introduction have been updated.
  • An introduction has been added for the Estrogen G protein-coupled receptor.

Useful links

FREE ONLINE BJP Guide to Receptors and Channels A laboratory handbook containing concise summaries, with key references, of the molecular, pharmacological and signal transduction properties of receptors, ion channels & transporters

HUGO Gene Nomenclature committee

Pharmacological reviews

IUPHAR Career Centre

We welcome all questions, comments and suggestions - Email us: curators@iuphar-db.org

© IUPHAR 2009

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Page last updated 23rd June 2009

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