Nomenclature: Androgen receptor

Systematic Nomenclature: NR3C4

Family: 3C. 3-Ketosteroid receptors

Annotation status:  image of a green circle Annotated and expert reviewed. Please contact us if you can help with updates. 

Contents

Gene and Protein Information
Species AA Chromosomal Location Gene Symbol Gene Name Reference
Human 920 Xq11.2-q12 AR androgen receptor 4,11
Mouse 899 X36.0cM Ar androgen receptor 12,36
Rat 902 Xq22 Ar androgen receptor 50
Previous and Unofficial Names
RP11-383C12.1
AIS
DHTR
HUMARA
HYSP1
KD
SBMA
SMAX1
TFM
Androgen
dihydrotestosterone receptor
AR
NR3C4
spinal and bulbar muscular atrophy
testicular feminization
Kennedy disease
Andr
Androgen receptor (Testicular feminization)
Androgen receptor (Testicular feminization) same as Tfm
androgen receptor
androgen receptor (Testicular feminization), same as Tfm
nuclear receptor subfamily 3 group C member 4
AW320017
Database Links
ChEMBL Target
DrugBank Target
Ensembl Gene
Entrez Gene
GeneCards
GenitoUrinary Development Molecular Anatomy Project
HomoloGene
Human Protein Reference Database
InterPro
KEGG Gene
NURSA Receptor
OMIM
Orphanet Gene
PharmGKB Gene
PhosphoSitePlus
RefSeq Nucleotide
RefSeq Protein
TreeFam
UniProtKB
Wikipedia
Selected 3D Structures
Image of receptor 3D structure from RCSB PDB
Description:  Androgen receptor- ligand binding domain
PDB Id:  3L3X
Ligand:  dihydrotestosterone   This ligand is endogenous
Resolution:  1.55Å
Species:  Human
References:  65
Natural/Endogenous Ligands
dihydrotestosterone
testosterone
Comments: dihydrotestosterone has greater potency than testosterone
Rank order of potency (Human)
dihydrotestosterone > testosterone
Agonists
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
dihydrotestosterone Hs Agonist 9.3 pKd 53
pKd 9.3 (Kd 5x10-10 M) [53]
testosterone propionate Hs Agonist 9.6 pKi 38
pKi 9.6 (Ki 2.5x10-10 M) [38]
fluoxymesterone Hs Agonist 8.24 pKi 21
pKi 8.24 (Ki 5.7x10-9 M) [21]
danazol Rn Agonist 8.0 pKi 5
pKi 8.0 (Ki 1x10-8 M) [5]
methyltestosterone Hs Full agonist 9.66 pEC50 1
pEC50 9.66 (EC50 2.2x10-10 M) Androgen receptor promoter activity in luciferase reporter assay [1]
Description: 22Rv1 human prostate cells transfected with hAR and luciferase reporter plasmid driven by the androgen response element.
methyltrienolone Hs Agonist <5.0 pEC50 58
pEC50 <5.0 (EC50 >1x10-5 M) [58]
mibolerone Hs Agonist 8.96 pIC50 17
pIC50 8.96 (IC50 1.1x10-9 M) [17]
mibolerone Rn Agonist 8.8 pIC50 11
pIC50 8.8 [11]
dihydrotestosterone Rn Agonist 8.65 pIC50 11
pIC50 8.65 [11]
androstenedione Rn Agonist 8.56 pIC50 11
pIC50 8.56 [11]
methyltrienolone Rn Agonist 8.51 pIC50 11
pIC50 8.51 [11]
testosterone Rn Agonist 7.8 pIC50 11
pIC50 7.8 [11]
[3H]dihydrotestosterone Hs Agonist - -
[3H]R1881 Hs Agonist - -
dromostanolone propionate Hs Agonist - -
ethylestrenol Hs Agonist - -
[3H]mibolerone Hs Agonist - -
nandrolone Hs Agonist - -
View species-specific agonist tables
Agonist Comments
Combined treatment with drostanolone propionate and 5-fluoracil significantly increased the complete remission rate of induced mammary carcinomas in rats, compared to 5-fluoracil alone [52].
In a study comparing the competitive binding (displacement of [3H]methyltrienolone) of various anabolic steroids to the AR of skeletal muscle (rat and rabbit) and prostate tissue (rat), the binding of ethylestrenol was too low to determine its relative binding affinity [46].
A study by Krieg et al (1976) examines the relative displaceable binding of nandrolone (aka 19-nortestosterone), testosterone and 5α-dihydrotestosterone to the rat androgen receptor [30].
Antagonists
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
mifepristone Hs Antagonist 9.19 pKi 56
pKi 9.19 (Ki 6.5x10-10 M) [56]
cyproterone acetate Hs Antagonist 7.85 pKi 20
pKi 7.85 (Ki 1.4x10-8 M) [20]
bicalutamide Hs Antagonist 7.72 pKi 28
pKi 7.72 (Ki 1.9x10-8 M) [28]
flutamide Hs Antagonist 5.43 pKi 57
pKi 5.43 (Ki 3.7x10-6 M) Displacement of 3[H] testosterone from wild-typr androgen receptors [57]
hydroxyflutamide Hs Antagonist 6.6 pEC50 58
pEC50 6.6 (EC50 2.54x10-7 M) [58]
PF0998425 Hs Antagonist 7.1 – 7.5 pIC50 32
pIC50 7.1 – 7.5 [32]
nilutamide Hs Antagonist 7.07 – 7.12 pIC50 48
pIC50 7.07 – 7.12 (IC50 8.5x10-8 – 7.5x10-8 M) [48]
enzalutamide Hs Antagonist - -
Antagonist Comments
Enzalutamide antagonises testosterone-induced androgen-dependent gene transcription and nuclear translocation of the androgen receptor in human prostate LnCaP cells [18].
DNA Binding
Structure:  Homodimer
HRE core sequence:  GGTACANNNTGTTCT
Response element:  GRE, Palindrome
DNA Binding Comments
NR3C1-4 receptors all bind to the same consensus sequence. Data indicate that sequences surrounding the response element may confer specificity to receptor binding.
Co-binding Partners
Name Interaction Effect Reference
HMGB Physical, Functional DNA binding 3,54
Hsp90 Physical Cellular localization, protein stability 15,39
Main Co-regulators
Name Activity Specific Ligand dependent AF-2 dependent Comments References
RNF14 Co-activator Yes Yes Yes 25-26,41
TGFB1I1 Co-activator Yes Yes Yes 13,40,42,62
RAN Co-activator Yes Yes Yes 22,62
NCOA2 Co-activator No Yes Yes Histone acetyl transferase, also a nucleating platform for recruitment of general coactivators (CBP, CARM1, p300) 16,27,61
NCOA4 Co-activator Yes Yes Yes Increases AR expression, protein stability, and nuclear translocation. 16,23,62
FHL2 Co-activator Yes Yes Yes Contains 4 1/2 LIM domains 6,43
Main Target Genes
Name Species Effect Technique Comments References
Pbsn Rat Activated Transient transfection 45
rsl Mouse Activated Transient transfection, EMSA 47
C3 Rat Activated Transient transfection, EMSA 51
human secretory component Human Activated Transient transfection, EMSA 19,55
KLK3 Human Activated ChIP, Transient transfection, EMSA, Footprint Also observed in rodents 9,64
Tissue Distribution
Bone marrow, mammary gland, muscle, prostate, stem cell, testis, preputial gland, scrotal skin, vagina
Expression level:  High
Species:  Rat
Technique:  Western blotting
References:  2
Functional Assays
SHBG increase in liver - androgen treatment increases expression of sex hormone binding globulin in liver
Species:  Human
Tissue:  hepatocarcinoma cell line HepG2
Response measured:  SHBG secretion
References:  31
Anabolic action in muscle - treatment of castrated rats with AR ligands possessing anabolic activity results in increased muscle mass.
Species:  Rat
Tissue:  skeletal muscle
Response measured:  weight of the levator ani muscle
References:  63
Prostate weight and seminal vessicle weight - treatment castrated rats with AR ligands possessing androgenic activity results in increased weight of the prostate and seminal vesicles.
Species:  Rat
Tissue:  prostate, seminal vesicles
Response measured:  weight of prostate and seminal vesicles
References:  63
Physiological Consequences of Altering Gene Expression
Insulin resistance - male mice lacking AR (-/y) display progressive reduced insulin sensitivity and impaired glucose tolerance
Species:  Mouse
Tissue: 
Technique:  targeted knock-out
References:  10,34-35
Infertility - male mice lacking expression of AR in the Sertoli cells display infertility with defective spermatogenesis and hypotestosteronemia
Species:  Mouse
Tissue: 
Technique:  targeted knock-out
References:  7
Phenotypes, Alleles and Disease Models Mouse data from MGI

Show »

Allele Composition & genetic background Accession Phenotype Id Phenotype Reference
ArTfm ArTfm/Y
STOCK Eda Atp7a/+ +
MGI:88064  MP:0005189 abnormal anogenital distance PMID: 5452809 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0005189 abnormal anogenital distance PMID: 12370412 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0009642 abnormal blood homeostasis PMID: 16981011 
Artm1Ska|Tg(CMV-cre)1Ipc Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
involves: C57BL/6 * CBA
MGI:2177164  MGI:88064  MP:0001259 abnormal body weight PMID: 12943692 
ArTfm ArTfm/Y
involves: STOCK Eda Atp7a
MGI:88064  MP:0000172 abnormal bone marrow cell number PMID: 9647203 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0008271 abnormal bone ossification PMID: 12370412 
Artm1.1Chc|Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Artm1.1Chc,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0000662 abnormal branching of the mammary ductal tree PMID: 14676301 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0000130 abnormal cancellous bone morphology PMID: 12370412 
Artm1Jdz|Tg(Pbsn-cre)20Fwan Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
involves: C57BL/6J * FVB/N
MGI:3717411  MGI:88064  MP:0002662 abnormal cauda epididymis morphology PMID: 18356274 
Artm1Jdz|Tg(Pbsn-cre)20Fwan Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
involves: C57BL/6J * FVB/N
MGI:3717411  MGI:88064  MP:0009697 abnormal copulation PMID: 18356274 
Artm1Jdz|Tg(Pbsn-cre)20Fwan Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
involves: C57BL/6J * FVB/N
MGI:3717411  MGI:88064  MP:0002661 abnormal corpus epididymis morphology PMID: 18356274 
ArTfm ArTfm/Y
involves: STOCK Eda Atp7a
MGI:88064  MP:0000245 abnormal erythropoiesis PMID: 9647203 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0009199 abnormal external male genitalia morphology PMID: 12370412 
Artm2Ska|Gli1+|Gli1tm3(cre/ERT2)Alj Artm2Ska/Y,Gli1tm3(cre/ERT2)Alj/Gli1+
involves: 129S6/SvEvTac * C57BL/6 * CBA
MGI:88064  MGI:95727  MP:0009199 abnormal external male genitalia morphology PMID: 19282366 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0009115 abnormal fat cell morphology PMID: 12370412  15919793 
ArTfm|Insl3tm1Imad ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad
involves: 129/Sv * CD-1 * STOCK Eda
MGI:108427  MGI:88064  MP:0001119 abnormal female reproductive system morphology PMID: 10319319 
ArTfm ArTfm/Y
STOCK Eda Atp7a/+ +
MGI:88064  MP:0001119 abnormal female reproductive system morphology PMID: 5452809 
Artm2Ska|Gli1+|Gli1tm3(cre/ERT2)Alj Artm2Ska/Y,Gli1tm3(cre/ERT2)Alj/Gli1+
involves: 129S6/SvEvTac * C57BL/6 * CBA
MGI:88064  MGI:95727  MP:0003553 abnormal foreskin morphology PMID: 19282366 
ArTfm ArTfm/Y
STOCK Eda Atp7a/+ +
MGI:88064  MP:0001929 abnormal gametogenesis PMID: 5452809 
ArTfm|Insl3tm1Imad ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad
involves: 129/Sv * CD-1 * STOCK Eda
MGI:108427  MGI:88064  MP:0005149 abnormal gubernaculum morphology PMID: 10319319 
Artm1Ska|Tg(CMV-cre)1Ipc Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
involves: C57BL/6 * CBA
MGI:2177164  MGI:88064  MP:0003921 abnormal heart left ventricle morphology PMID: 15961403 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0001764 abnormal homeostasis PMID: 12370412 
Artm1.1Chc|Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Artm1.1Chc,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0001882 abnormal lactation PMID: 14676301 
ArTfm ArTfm/Y
STOCK Eda Atp7a/+ +
MGI:88064  MP:0002786 abnormal Leydig cell morphology PMID: 5452809 
ArTfm ArTfm/Y
Not Specified
MGI:88064  MP:0002786 abnormal Leydig cell morphology PMID: 11090455 
Artm1Verh|Tg(AMH-cre)1Flor Artm1Verh/Y,Tg(AMH-cre)1Flor/0
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:2450303  MGI:88064  MP:0002786 abnormal Leydig cell morphology PMID: 15919750 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0002786 abnormal Leydig cell morphology PMID: 12370412 
Artm1Jdz|Tg(Abpa-cre)1Cmal Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/0
involves: 129X1/SvJ * C57BL/6 * DBA/2
MGI:4431034  MGI:88064  MP:0002786 abnormal Leydig cell morphology PMID: 19574395 
Artm1Jdz|Tg(AMH-cre)1Flor Artm1Jdz/Y,Tg(AMH-cre)1Flor/0
involves: 129X1/SvJ * C57BL/6 * SJL
MGI:2450303  MGI:88064  MP:0002786 abnormal Leydig cell morphology PMID: 19574395 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0000133 abnormal long bone metaphysis morphology PMID: 12370412 
Amhtm1Bhr|ArTfm Amhtm1Bhr/Amhtm1Bhr,ArTfm/Y
either: (involves 129P3/J * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6)
MGI:88006  MGI:88064  MP:0001145 abnormal male reproductive system morphology PMID: 7954809 
ArTfm|Insl3tm1Imad ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad
involves: 129/Sv * CD-1 * STOCK Eda
MGI:108427  MGI:88064  MP:0001145 abnormal male reproductive system morphology PMID: 10319319 
ArTfm ArTfm/Y
STOCK Eda Atp7a/+ +
MGI:88064  MP:0001145 abnormal male reproductive system morphology PMID: 5452809 
Artm1.1Verh Artm1.1Verh/Y
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:88064  MP:0001145 abnormal male reproductive system morphology PMID: 14745012 
Artm1.1Jdz Artm1.1Jdz/Y
B6.129X1-Ar
MGI:88064  MP:0001145 abnormal male reproductive system morphology PMID: 16326839 
Artm1.1Chc|Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Artm1.1Chc,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0000627 abnormal mammary gland morphology PMID: 14676301 
Artm1Chc|Tg(AMH-cre)1Flor Artm1Chc/Y,Tg(AMH-cre)1Flor/0
involves: 129S/SvEv * C57BL/6 * SJL
MGI:2450303  MGI:88064  MP:0001930 abnormal meiosis PMID: 17142319 
Amhr2+|Amhr2tm3(cre)Bhr|Artm1Chc Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y
involves: 129S/SvEv * C57BL/6
MGI:105062  MGI:88064  MP:0001930 abnormal meiosis PMID: 17142319 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0004145 abnormal muscle electrophysiology PMID: 16981011 
ArTfm ArTfm/Y
involves: STOCK Eda Atp7a
MGI:88064  MP:0008250 abnormal myeloid leukocyte morphology PMID: 9647203 
Artm1Ska|Tg(CMV-cre)1Ipc Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
involves: C57BL/6 * CBA
MGI:2177164  MGI:88064  MP:0000278 abnormal myocardial fiber morphology PMID: 15961403 
Artm1.1Chc|Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Artm1.1Chc,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0001382 abnormal nursing PMID: 14676301 
Artm1Ska|Tg(CMV-cre)1Ipc Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
involves: C57BL/6 * CBA
MGI:2177164  MGI:88064  MP:0005187 abnormal penis morphology PMID: 12943692 
Artm1.1Verh Artm1.1Verh/Y
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:88064  MP:0006420 abnormal peritubular myoid cell morphology PMID: 14745012 
Artm1.1Verh Artm1.1Verh/Y
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:88064  MP:0001731 abnormal postnatal growth PMID: 14745012 
Artm1Jdz|Tg(Pbsn-cre)20Fwan Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
involves: 129X1/SvJ * C57BL/6 * FVB/N
MGI:3717411  MGI:88064  MP:0001163 abnormal prostate gland anterior lobe morphology PMID: 17317769 
Artm1Jdz|Tg(Pbsn-cre)20Fwan Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
involves: 129X1/SvJ * C57BL/6 * FVB/N
MGI:3717411  MGI:88064  MP:0001168 abnormal prostate gland epithelium morphology PMID: 17317769 
Artm1Chc|Tg(Pbsn-cre)4Prb Artm1Chc/Y,Tg(Pbsn-cre)4Prb/0
involves: 129S/SvEv * C57BL/6 * DBA/2
MGI:2388169  MGI:88064  MP:0001168 abnormal prostate gland epithelium morphology PMID: 17652515 
Artm1Jdz|Tg(Pbsn-cre)20Fwan Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
involves: 129X1/SvJ * C57BL/6 * FVB/N
MGI:3717411  MGI:88064  MP:0001158 abnormal prostate gland morphology PMID: 17317769 
Artm1Chc|Tg(Pbsn-cre)4Prb Artm1Chc/Y,Tg(Pbsn-cre)4Prb/0
involves: 129S/SvEv * C57BL/6 * DBA/2
MGI:2388169  MGI:88064  MP:0001158 abnormal prostate gland morphology PMID: 17652515 
Artm2Ska|Gli1+|Gli1tm3(cre/ERT2)Alj Artm2Ska/Y,Gli1tm3(cre/ERT2)Alj/Gli1+
involves: 129S6/SvEvTac * C57BL/6 * CBA
MGI:88064  MGI:95727  MP:0003936 abnormal reproductive system development PMID: 19282366 
Artm1Ska|Tg(CMV-cre)1Ipc Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
involves: C57BL/6 * CBA
MGI:2177164  MGI:88064  MP:0001919 abnormal reproductive system physiology PMID: 12943692 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0002669 abnormal scrotum morphology PMID: 12370412 
Amhtm1Bhr|ArTfm Amhtm1Bhr/Amhtm1Bhr,ArTfm/Y
either: (involves 129P3/J * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6)
MGI:88006  MGI:88064  MP:0002212 abnormal secondary sex determination PMID: 7954809 
ArTfm|Insl3tm1Imad ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad
involves: 129/Sv * CD-1 * STOCK Eda
MGI:108427  MGI:88064  MP:0002212 abnormal secondary sex determination PMID: 10319319 
ArTfm ArTfm/Y
STOCK Eda Atp7a/+ +
MGI:88064  MP:0002212 abnormal secondary sex determination PMID: 5452809 
Artm1.1Verh Artm1.1Verh/Y
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:88064  MP:0002212 abnormal secondary sex determination PMID: 14745012 
ArTfm-Jms ArTfm-Jms/Y
C57BL/6JJms
MGI:88064  MP:0002212 abnormal secondary sex determination PMID: 7967466 
Artm1Jdz|Tg(Pbsn-cre)20Fwan Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
involves: 129X1/SvJ * C57BL/6 * FVB/N
MGI:3717411  MGI:88064  MP:0002059 abnormal seminal vesicle morphology PMID: 17317769 
Artm1Jdz|Tg(Pbsn-cre)20Fwan Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
involves: C57BL/6J * FVB/N
MGI:3717411  MGI:88064  MP:0002059 abnormal seminal vesicle morphology PMID: 18356274 
ArTfm ArTfm/Y
involves: STOCK Eda Atp7a
MGI:88064  MP:0002216 abnormal seminiferous tubule morphology PMID: 18401008 
Artm1Reb Artm1Reb/Y
involves: 129S4/SvJaeSor
MGI:88064  MP:0002216 abnormal seminiferous tubule morphology PMID: 14701682 
Artm1Reb|Tg(Amh-cre)8815Reb Artm1Reb/Y,Tg(Amh-cre)8815Reb/?
involves: 129S4/SvJaeSor * FVB/N
MGI:3044682  MGI:88064  MP:0002216 abnormal seminiferous tubule morphology PMID: 14701682 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0002216 abnormal seminiferous tubule morphology PMID: 16981011 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0002216 abnormal seminiferous tubule morphology PMID: 17142319 
Artm1Chc|Tg(AMH-cre)1Flor Artm1Chc/Y,Tg(AMH-cre)1Flor/0
involves: 129S/SvEv * C57BL/6 * SJL
MGI:2450303  MGI:88064  MP:0002216 abnormal seminiferous tubule morphology PMID: 15107499  17142319 
Amhr2+|Amhr2tm3(cre)Bhr|Artm1Chc Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y
involves: 129S/SvEv * C57BL/6
MGI:105062  MGI:88064  MP:0002216 abnormal seminiferous tubule morphology PMID: 17142319 
ArTfm|Tg(TSPY)9Jshm ArTfm/Y,Tg(TSPY)9Jshm/0
involves: NMRI * STOCK Eda Atp7a
MGI:3775643  MGI:88064  MP:0002216 abnormal seminiferous tubule morphology PMID: 18401008 
ArTfm ArTfm/Y
involves: NMRI * STOCK Eda Atp7a
MGI:88064  MP:0002216 abnormal seminiferous tubule morphology PMID: 18401008 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0002784 abnormal Sertoli cell morphology PMID: 16400023 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0002784 abnormal Sertoli cell morphology PMID: 12370412  17142319 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0003084 abnormal skeletal muscle fiber morphology PMID: 16981011 
ArTfm ArTfm/Y
STOCK Eda Atp7a/+ +
MGI:88064  MP:0002557 abnormal social/conspecific interaction PMID: 5452809 
Artm1Verh|Tg(AMH-cre)1Flor Artm1Verh/Y,Tg(AMH-cre)1Flor/0
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:2450303  MGI:88064  MP:0006380 abnormal spermatid morphology PMID: 14745012 
Artm1Verh|Tg(AMH-cre)1Flor Artm1Verh/Y,Tg(AMH-cre)1Flor/0
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:2450303  MGI:88064  MP:0006379 abnormal spermatocyte morphology PMID: 14745012 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0006379 abnormal spermatocyte morphology PMID: 17142319 
ArTfm ArTfm/Y
Not Specified
MGI:88064  MP:0001156 abnormal spermatogenesis PMID: 11090455 
Artm1.1Verh Artm1.1Verh/Y
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:88064  MP:0001156 abnormal spermatogenesis PMID: 14745012 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0001156 abnormal spermatogenesis PMID: 16400023 
Artm1Chc|Tg(AMH-cre)1Flor Artm1Chc/Y,Tg(AMH-cre)1Flor/0
involves: 129S/SvEv * C57BL/6 * SJL
MGI:2450303  MGI:88064  MP:0001156 abnormal spermatogenesis PMID: 15107499 
Artm1Jdz|Tg(Abpa-cre)1Cmal Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/0
involves: 129X1/SvJ * C57BL/6 * DBA/2
MGI:4431034  MGI:88064  MP:0001156 abnormal spermatogenesis PMID: 19574395 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0006378 abnormal spermatogonia morphology PMID: 12370412 
Artm1Jdz|Tg(Pbsn-cre)20Fwan Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
involves: C57BL/6J * FVB/N
MGI:3717411  MGI:88064  MP:0008892 abnormal sperm flagellum morphology PMID: 18356274 
Artm1Jdz|Tg(Pbsn-cre)20Fwan Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
involves: C57BL/6J * FVB/N
MGI:3717411  MGI:88064  MP:0002673 abnormal sperm number PMID: 18356274 
Artm1Jdz|Tg(Pbsn-cre)20Fwan Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
involves: C57BL/6J * FVB/N
MGI:3717411  MGI:88064  MP:0004543 abnormal sperm physiology PMID: 18356274 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0000955 abnormal spinal cord morphology PMID: 16981011 
ArTfm ArTfm/Y
Not Specified
MGI:88064  MP:0001146 abnormal testis morphology PMID: 11090455 
Artm1Reb Artm1Reb/Y
involves: 129S4/SvJaeSor
MGI:88064  MP:0001146 abnormal testis morphology PMID: 14701682 
Artm1Reb|Tg(Amh-cre)8815Reb Artm1Reb/Y,Tg(Amh-cre)8815Reb/?
involves: 129S4/SvJaeSor * FVB/N
MGI:3044682  MGI:88064  MP:0001146 abnormal testis morphology PMID: 14701682 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0001146 abnormal testis morphology PMID: 16400023 
Artm1.1Jdz Artm1.1Jdz/Y
B6.129X1-Ar
MGI:88064  MP:0001146 abnormal testis morphology PMID: 16326839 
Artm1.1Jdz Artm1.1Jdz/Y
involves: 129X1/SvJ * C57BL/6
MGI:88064  MP:0001146 abnormal testis morphology PMID: 17317769 
Artm1Jdz|Tg(Abpa-cre)1Cmal Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/Tg(Abpa-cre)1Cmal
involves: 129X1/SvJ * C57BL/6 * DBA/2
MGI:4431034  MGI:88064  MP:0001146 abnormal testis morphology PMID: 19574395 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0009643 abnormal urine homeostasis PMID: 16400023 
Ar+|Artm4(AR)Dmr Artm4(AR)Dmr/Ar+
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0009643 abnormal urine homeostasis PMID: 16981011 
Amhtm1Bhr|ArTfm Amhtm1Bhr/Amhtm1Bhr,ArTfm/Y
either: (involves 129P3/J * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6)
MGI:88006  MGI:88064  MP:0004727 absent epididymis PMID: 7954809 
ArTfm|Insl3tm1Imad ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad
involves: 129/Sv * CD-1 * STOCK Eda
MGI:108427  MGI:88064  MP:0004727 absent epididymis PMID: 10319319 
ArTfm ArTfm/Y
STOCK Eda Atp7a/+ +
MGI:88064  MP:0004727 absent epididymis PMID: 5452809 
Artm1Ska|Tg(CMV-cre)1Ipc Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
involves: C57BL/6 * CBA
MGI:2177164  MGI:88064  MP:0004727 absent epididymis PMID: 12943692 
Artm1.1Verh Artm1.1Verh/Y
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:88064  MP:0004727 absent epididymis PMID: 14745012 
Artm1.1Jdz Artm1.1Jdz/Y
involves: 129X1/SvJ * C57BL/6
MGI:88064  MP:0004727 absent epididymis PMID: 17317769 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0004727 absent epididymis PMID: 12370412 
Artm1.1Chc Artm1.1Chc/Y
involves: 129S/SvEv * C57BL/6 * FVB/N
MGI:88064  MP:0004727 absent epididymis PMID: 15107499 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0009204 absent external male genitalia PMID: 12370412 
Artm1Ska|Tg(CMV-cre)1Ipc Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
involves: C57BL/6 * CBA
MGI:2177164  MGI:88064  MP:0001159 absent prostate gland PMID: 12943692 
Artm1.1Jdz Artm1.1Jdz/Y
B6.129X1-Ar
MGI:88064  MP:0001159 absent prostate gland PMID: 16326839 
Artm1.1Jdz Artm1.1Jdz/Y
involves: 129X1/SvJ * C57BL/6
MGI:88064  MP:0001159 absent prostate gland PMID: 17317769 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0001159 absent prostate gland PMID: 12370412 
Artm1.1Chc Artm1.1Chc/Y
involves: 129S/SvEv * C57BL/6 * FVB/N
MGI:88064  MP:0001159 absent prostate gland PMID: 15107499 
Artm1.1Jdz Artm1.1Jdz/Y
involves: 129X1/SvJ * C57BL/6
MGI:88064  MP:0002670 absent scrotum PMID: 17317769 
Artm1Ska|Tg(CMV-cre)1Ipc Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
involves: C57BL/6 * CBA
MGI:2177164  MGI:88064  MP:0003642 absent seminal vesicle PMID: 12943692 
Artm1.1Verh Artm1.1Verh/Y
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:88064  MP:0003642 absent seminal vesicle PMID: 14745012  15919750 
Artm1.1Jdz Artm1.1Jdz/Y
B6.129X1-Ar
MGI:88064  MP:0003642 absent seminal vesicle PMID: 16326839 
Artm1.1Jdz Artm1.1Jdz/Y
involves: 129X1/SvJ * C57BL/6
MGI:88064  MP:0003642 absent seminal vesicle PMID: 17317769 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0003642 absent seminal vesicle PMID: 12370412 
Artm1.1Chc Artm1.1Chc/Y
involves: 129S/SvEv * C57BL/6 * FVB/N
MGI:88064  MP:0003642 absent seminal vesicle PMID: 15107499 
Amhtm1Bhr|ArTfm Amhtm1Bhr/Amhtm1Bhr,ArTfm/Y
either: (involves 129P3/J * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6)
MGI:88006  MGI:88064  MP:0003557 absent vas deferens PMID: 7954809 
ArTfm|Insl3tm1Imad ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad
involves: 129/Sv * CD-1 * STOCK Eda
MGI:108427  MGI:88064  MP:0003557 absent vas deferens PMID: 10319319 
ArTfm ArTfm/Y
STOCK Eda Atp7a/+ +
MGI:88064  MP:0003557 absent vas deferens PMID: 5452809 
Artm1Ska|Tg(CMV-cre)1Ipc Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
involves: C57BL/6 * CBA
MGI:2177164  MGI:88064  MP:0003557 absent vas deferens PMID: 12943692 
Artm1.1Verh Artm1.1Verh/Y
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:88064  MP:0003557 absent vas deferens PMID: 14745012 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0003557 absent vas deferens PMID: 12370412 
Artm1.1Verh Artm1.1Verh/Y
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:88064  MP:0009073 absent Wolffian ducts PMID: 14745012 
Artm1.1Chc Artm1.1Chc/Y
involves: 129S/SvEv * C57BL/6 * FVB/N
MGI:88064  MP:0003448 altered tumor morphology PMID: 17406000 
ArTfm ArTfm/Y
STOCK Eda Atp7a/+ +
MGI:88064  MP:0008261 arrest of male meiosis PMID: 5452809 
ArTfm ArTfm/Y
involves: STOCK Eda Atp7a
MGI:88064  MP:0008261 arrest of male meiosis PMID: 18401008 
Artm1Verh|Tg(AMH-cre)1Flor Artm1Verh/Y,Tg(AMH-cre)1Flor/0
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:2450303  MGI:88064  MP:0008261 arrest of male meiosis PMID: 14745012 
Artm1.1Reb Artm1.1Reb/Y
involves: 129S4/SvJaeSor * C57BL/6 * DBA/2J
MGI:88064  MP:0008261 arrest of male meiosis PMID: 14701682 
Artm1.1Jdz Artm1.1Jdz/Y
B6.129X1-Ar
MGI:88064  MP:0008261 arrest of male meiosis PMID: 16326839 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0008261 arrest of male meiosis PMID: 17142319 
Artm1Chc|Tg(AMH-cre)1Flor Artm1Chc/Y,Tg(AMH-cre)1Flor/0
involves: 129S/SvEv * C57BL/6 * SJL
MGI:2450303  MGI:88064  MP:0008261 arrest of male meiosis PMID: 15107499  17142319 
Amhr2+|Amhr2tm3(cre)Bhr|Artm1Chc Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y
involves: 129S/SvEv * C57BL/6
MGI:105062  MGI:88064  MP:0008261 arrest of male meiosis PMID: 17142319 
ArTfm|Tg(TSPY)9Jshm ArTfm/Y,Tg(TSPY)9Jshm/0
involves: NMRI * STOCK Eda Atp7a
MGI:3775643  MGI:88064  MP:0008261 arrest of male meiosis PMID: 18401008 
ArTfm ArTfm/Y
involves: NMRI * STOCK Eda Atp7a
MGI:88064  MP:0008261 arrest of male meiosis PMID: 18401008 
Amhtm1Bhr|ArTfm Amhtm1Bhr/Amhtm1Bhr,ArTfm/Y
either: (involves 129P3/J * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6)
MGI:88006  MGI:88064  MP:0001155 arrest of spermatogenesis PMID: 7954809 
Artm1Ska|Tg(CMV-cre)1Ipc Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
involves: C57BL/6 * CBA
MGI:2177164  MGI:88064  MP:0001155 arrest of spermatogenesis PMID: 12943692 
Artm1Verh|Tg(AMH-cre)1Flor Artm1Verh/Y,Tg(AMH-cre)1Flor/0
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:2450303  MGI:88064  MP:0001155 arrest of spermatogenesis PMID: 14745012 
Artm1.1Jdz Artm1.1Jdz/Y
B6.129X1-Ar
MGI:88064  MP:0001155 arrest of spermatogenesis PMID: 16326839 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0001155 arrest of spermatogenesis PMID: 12370412 
Artm1.1Chc Artm1.1Chc/Y
involves: 129S/SvEv * C57BL/6 * FVB/N
MGI:88064  MP:0001155 arrest of spermatogenesis PMID: 15107499 
Amhr2+|Amhr2tm3(cre)Bhr|Artm1Chc Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y
involves: 129S/SvEv * C57BL/6
MGI:105062  MGI:88064  MP:0001155 arrest of spermatogenesis PMID: 17142319 
Artm1Jdz|Tg(Abpa-cre)1Cmal Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/Tg(Abpa-cre)1Cmal
involves: 129X1/SvJ * C57BL/6 * DBA/2
MGI:4431034  MGI:88064  MP:0001155 arrest of spermatogenesis PMID: 19574395 
Artm1Jdz|Tg(AMH-cre)1Flor Artm1Jdz/Y,Tg(AMH-cre)1Flor/0
involves: 129X1/SvJ * C57BL/6 * SJL
MGI:2450303  MGI:88064  MP:0001155 arrest of spermatogenesis PMID: 19574395 
Artm1Jdz|Tg(AMH-cre)1Flor Artm1Jdz/Y,Tg(AMH-cre)1Flor/Tg(AMH-cre)1Flor
involves: 129X1/SvJ * C57BL/6 * SJL
MGI:2450303  MGI:88064  MP:0001155 arrest of spermatogenesis PMID: 19574395 
Artm1.1Verh Artm1.1Verh/Y
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:88064  MP:0005159 azoospermia PMID: 14745012 
Artm1Verh|Tg(AMH-cre)1Flor Artm1Verh/Y,Tg(AMH-cre)1Flor/0
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:2450303  MGI:88064  MP:0005159 azoospermia PMID: 14745012 
Artm1Reb|Tg(Amh-cre)8815Reb Artm1Reb/Y,Tg(Amh-cre)8815Reb/?
involves: 129S4/SvJaeSor * FVB/N
MGI:3044682  MGI:88064  MP:0005159 azoospermia PMID: 14701682 
Artm1.1Jdz Artm1.1Jdz/Y
B6.129X1-Ar
MGI:88064  MP:0005159 azoospermia PMID: 16326839 
Artm1Chc|Tg(AMH-cre)1Flor Artm1Chc/Y,Tg(AMH-cre)1Flor/0
involves: 129S/SvEv * C57BL/6 * SJL
MGI:2450303  MGI:88064  MP:0005159 azoospermia PMID: 15107499  17142319 
Amhr2+|Amhr2tm3(cre)Bhr|Artm1Chc Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y
involves: 129S/SvEv * C57BL/6
MGI:105062  MGI:88064  MP:0005159 azoospermia PMID: 17142319 
Artm1Ska|Tg(CMV-cre)1Ipc Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
involves: C57BL/6 * CBA
MGI:2177164  MGI:88064  MP:0003534 blind vagina PMID: 12943692 
Artm1Ska|Tg(CMV-cre)1Ipc Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
involves: C57BL/6 * CBA
MGI:2177164  MGI:88064  MP:0005608 cardiac interstitial fibrosis PMID: 15961403 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0009404 centrally nucleated skeletal muscle fibers PMID: 16981011 
Artm1Jdz|Tg(Pbsn-cre)20Fwan Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
involves: C57BL/6J * FVB/N
MGI:3717411  MGI:88064  MP:0009238 coiled sperm flagellum PMID: 18356274 
Amhtm1Bhr|ArTfm Amhtm1Bhr/Amhtm1Bhr,ArTfm/Y
either: (involves 129P3/J * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6)
MGI:88006  MGI:88064  MP:0002286 cryptorchism PMID: 7954809 
ArTfm|Insl3tm1Imad ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad
involves: 129/Sv * CD-1 * STOCK Eda
MGI:108427  MGI:88064  MP:0002286 cryptorchism PMID: 10319319 
ArTfm ArTfm/Y
STOCK Eda Atp7a/+ +
MGI:88064  MP:0002286 cryptorchism PMID: 5452809 
Artm1Ska|Tg(CMV-cre)1Ipc Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
involves: C57BL/6 * CBA
MGI:2177164  MGI:88064  MP:0002286 cryptorchism PMID: 12943692 
Artm1.1Verh Artm1.1Verh/Y
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:88064  MP:0002286 cryptorchism PMID: 14745012 
Artm1.1Reb Artm1.1Reb/Y
involves: 129S4/SvJaeSor * C57BL/6 * DBA/2J
MGI:88064  MP:0002286 cryptorchism PMID: 14701682 
Artm1.1Jdz Artm1.1Jdz/Y
B6.129X1-Ar
MGI:88064  MP:0002286 cryptorchism PMID: 16326839 
Artm1.1Jdz Artm1.1Jdz/Y
involves: 129X1/SvJ * C57BL/6
MGI:88064  MP:0002286 cryptorchism PMID: 17317769 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0002286 cryptorchism PMID: 12370412  17142319 
ArTfm|Tg(TSPY)9Jshm ArTfm/Y,Tg(TSPY)9Jshm/0
involves: NMRI * STOCK Eda Atp7a
MGI:3775643  MGI:88064  MP:0002286 cryptorchism PMID: 18401008 
ArTfm ArTfm/Y
involves: NMRI * STOCK Eda Atp7a
MGI:88064  MP:0002286 cryptorchism PMID: 18401008 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0004893 decreased adiponectin level PMID: 15919793 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0001265 decreased body size PMID: 16981011 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0001262 decreased body weight PMID: 16981011 
Artm1.1Jdz Artm1.1Jdz/Y
B6.129X1-Ar
MGI:88064  MP:0001262 decreased body weight PMID: 16326839 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0001262 decreased body weight PMID: 12370412  15919793 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0002790 decreased circulating follicle stimulating hormone level PMID: 16400023 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0002780 decreased circulating testosterone level PMID: 16981011 
Artm1.1Jdz Artm1.1Jdz/Y
B6.129X1-Ar
MGI:88064  MP:0002780 decreased circulating testosterone level PMID: 16326839 
Artm1.1Jdz Artm1.1Jdz/Y
involves: 129X1/SvJ * C57BL/6
MGI:88064  MP:0002780 decreased circulating testosterone level PMID: 17317769 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0002780 decreased circulating testosterone level PMID: 12370412  15919793  17142319 
Artm1Chc|Tg(AMH-cre)1Flor Artm1Chc/Y,Tg(AMH-cre)1Flor/0
involves: 129S/SvEv * C57BL/6 * SJL
MGI:2450303  MGI:88064  MP:0002780 decreased circulating testosterone level PMID: 15107499  17142319 
Artm1.1Chc Artm1.1Chc/Y
involves: 129S/SvEv * C57BL/6 * FVB/N
MGI:88064  MP:0002780 decreased circulating testosterone level PMID: 15107499 
Amhr2+|Amhr2tm3(cre)Bhr|Artm1Chc Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y
involves: 129S/SvEv * C57BL/6
MGI:105062  MGI:88064  MP:0002780 decreased circulating testosterone level PMID: 17142319 
Artm1Verh|Tg(AMH-cre)1Flor Artm1Verh/Y,Tg(AMH-cre)1Flor/0
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:2450303  MGI:88064  MP:0004929 decreased epididymis weight PMID: 14745012 
Artm1Fcl Artm1Fcl/Y
involves: 129S2/SvPas * C57BL/6
MGI:88064  MP:0004929 decreased epididymis weight PMID: 17360365 
Artm1Jdz|Tg(Pbsn-cre)20Fwan Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
involves: 129X1/SvJ * C57BL/6 * FVB/N
MGI:3717411  MGI:88064  MP:0004929 decreased epididymis weight PMID: 17317769 
Artm1Fcl Artm1Fcl/Y
involves: 129S2/SvPas * C57BL/6
MGI:88064  MP:0002209 decreased germ cell number PMID: 17360365 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0010053 decreased grip strength PMID: 16981011 
Ar+|Artm4(AR)Dmr Artm4(AR)Dmr/Ar+
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0010053 decreased grip strength PMID: 16981011 
Artm1Ska|Tg(CMV-cre)1Ipc Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
involves: C57BL/6 * CBA
MGI:2177164  MGI:88064  MP:0002834 decreased heart weight PMID: 15961403 
Artm1.1Chc Artm1.1Chc/Y
involves: 129S/SvEv * C57BL/6 * FVB/N
MGI:88064  MP:0004502 decreased incidence of chemically-induced tumors PMID: 17406000 
Artm1.1Chc Artm1.1Chc/Artm1.1Chc
involves: 129S/SvEv * C57BL/6 * FVB/N
MGI:88064  MP:0004502 decreased incidence of chemically-induced tumors PMID: 17406000 
Artm1Fcl Artm1Fcl/Y
involves: 129S2/SvPas * C57BL/6
MGI:88064  MP:0001935 decreased litter size PMID: 17360365 
Ar+|Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Ar+,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0001935 decreased litter size PMID: 12370412 
Artm1.1Chc|Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Artm1.1Chc,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0001935 decreased litter size PMID: 12370412 
Artm1Jdz|Tg(Pbsn-cre)20Fwan Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
involves: C57BL/6J * FVB/N
MGI:3717411  MGI:88064  MP:0001935 decreased litter size PMID: 18356274 
Artm1.1Verh Artm1.1Verh/Y
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:88064  MP:0004901 decreased male germ cell number PMID: 14745012 
Artm1Verh|Tg(AMH-cre)1Flor Artm1Verh/Y,Tg(AMH-cre)1Flor/0
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:2450303  MGI:88064  MP:0004901 decreased male germ cell number PMID: 14745012 
Artm1.1Jdz Artm1.1Jdz/Y
B6.129X1-Ar
MGI:88064  MP:0004901 decreased male germ cell number PMID: 16326839 
Artm1Chc|Tg(AMH-cre)1Flor Artm1Chc/Y,Tg(AMH-cre)1Flor/0
involves: 129S/SvEv * C57BL/6 * SJL
MGI:2450303  MGI:88064  MP:0004901 decreased male germ cell number PMID: 15107499 
Artm1.1Chc|Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Artm1.1Chc,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0004856 decreased ovary weight PMID: 14676301 
Artm1.1Chc|Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Artm1.1Chc,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0009066 decreased oviduct weight PMID: 14676301 
Artm1Fcl Artm1Fcl/Y
involves: 129S2/SvPas * C57BL/6
MGI:88064  MP:0004962 decreased prostate gland weight PMID: 17360365 
Artm1Jdz|Tg(Pbsn-cre)20Fwan Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
involves: 129X1/SvJ * C57BL/6 * FVB/N
MGI:3717411  MGI:88064  MP:0004962 decreased prostate gland weight PMID: 17317769 
Artm1Reb Artm1Reb/Y
involves: 129S4/SvJaeSor
MGI:88064  MP:0004910 decreased seminal vesicle weight PMID: 14701682 
Artm1Reb|Tg(Amh-cre)8815Reb Artm1Reb/Y,Tg(Amh-cre)8815Reb/?
involves: 129S4/SvJaeSor * FVB/N
MGI:3044682  MGI:88064  MP:0004910 decreased seminal vesicle weight PMID: 14701682 
Artm1Fcl Artm1Fcl/Y
involves: 129S2/SvPas * C57BL/6
MGI:88064  MP:0004910 decreased seminal vesicle weight PMID: 17360365 
Artm1Jdz|Tg(Pbsn-cre)20Fwan Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
involves: 129X1/SvJ * C57BL/6 * FVB/N
MGI:3717411  MGI:88064  MP:0004910 decreased seminal vesicle weight PMID: 17317769 
Artm1Jdz|Tg(Pbsn-cre)20Fwan Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
involves: C57BL/6J * FVB/N
MGI:3717411  MGI:88064  MP:0004910 decreased seminal vesicle weight PMID: 18356274 
Artm1.1Verh Artm1.1Verh/Y
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:88064  MP:0004852 decreased testis weight PMID: 14745012  15919750 
Artm1Verh|Tg(AMH-cre)1Flor Artm1Verh/Y,Tg(AMH-cre)1Flor/0
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:2450303  MGI:88064  MP:0004852 decreased testis weight PMID: 14745012  15919750 
Artm1Reb Artm1Reb/Y
involves: 129S4/SvJaeSor
MGI:88064  MP:0004852 decreased testis weight PMID: 14701682 
Artm1Reb|Tg(Amh-cre)8815Reb Artm1Reb/Y,Tg(Amh-cre)8815Reb/?
involves: 129S4/SvJaeSor * FVB/N
MGI:3044682  MGI:88064  MP:0004852 decreased testis weight PMID: 14701682 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0004852 decreased testis weight PMID: 16400023 
Artm1Fcl Artm1Fcl/Y
involves: 129S2/SvPas * C57BL/6
MGI:88064  MP:0004852 decreased testis weight PMID: 17360365 
Artm1.1Jdz Artm1.1Jdz/Y
B6.129X1-Ar
MGI:88064  MP:0004852 decreased testis weight PMID: 16326839 
Artm1.1Jdz Artm1.1Jdz/Y
involves: 129X1/SvJ * C57BL/6
MGI:88064  MP:0004852 decreased testis weight PMID: 17317769 
Artm1Chc|Tg(AMH-cre)1Flor Artm1Chc/Y,Tg(AMH-cre)1Flor/0
involves: 129S/SvEv * C57BL/6 * SJL
MGI:2450303  MGI:88064  MP:0004852 decreased testis weight PMID: 15107499 
Artm1Jdz|Tg(Abpa-cre)1Cmal Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/0
involves: 129X1/SvJ * C57BL/6 * DBA/2
MGI:4431034  MGI:88064  MP:0004852 decreased testis weight PMID: 19574395 
Artm1Jdz|Tg(Abpa-cre)1Cmal Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/Tg(Abpa-cre)1Cmal
involves: 129X1/SvJ * C57BL/6 * DBA/2
MGI:4431034  MGI:88064  MP:0004852 decreased testis weight PMID: 19574395 
Artm1Jdz|Tg(Abpa-cre)1Cmal|Tg(AMH-cre)1Flor Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/0,Tg(AMH-cre)1Flor/0
involves: 129X1/SvJ * C57BL/6 * DBA/2 * SJL
MGI:2450303  MGI:4431034  MGI:88064  MP:0004852 decreased testis weight PMID: 19574395 
Artm1Jdz|Tg(AMH-cre)1Flor Artm1Jdz/Y,Tg(AMH-cre)1Flor/0
involves: 129X1/SvJ * C57BL/6 * SJL
MGI:2450303  MGI:88064  MP:0004852 decreased testis weight PMID: 19574395 
Artm1Jdz|Tg(AMH-cre)1Flor Artm1Jdz/Y,Tg(AMH-cre)1Flor/Tg(AMH-cre)1Flor
involves: 129X1/SvJ * C57BL/6 * SJL
MGI:2450303  MGI:88064  MP:0004852 decreased testis weight PMID: 19574395 
Artm1Jdz|Tg(CMV-cre)1Cgn Artm1Jdz/Y,Tg(CMV-cre)1Cgn/0
involves: 129X1/SvJ * BALB/cJ
MGI:2176179  MGI:88064  MP:0004852 decreased testis weight PMID: 19574395 
Artm3(AR)Dmr|Tg(TRAMP)8247Ng Artm3(AR)Dmr/Y,Tg(TRAMP)8247Ng/0
involves: 129S1/Sv * C57BL/6
MGI:2680364  MGI:88064  MP:0002052 decreased tumor incidence PMID: 16601069 
Artm1.1Chc|Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Artm1.1Chc,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0004905 decreased uterus weight PMID: 14676301 
Artm1Ska|Tg(CMV-cre)1Ipc Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
involves: C57BL/6 * CBA
MGI:2177164  MGI:88064  MP:0005598 decreased ventricle muscle contractility PMID: 15961403 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0000539 distended urinary bladder PMID: 16981011 
Artm1Chc|Tg(Pbsn-cre)4Prb Artm1Chc/Y,Tg(Pbsn-cre)4Prb/0
involves: 129S/SvEv * C57BL/6 * DBA/2
MGI:2388169  MGI:88064  MP:0004958 enlarged prostate gland PMID: 17652515 
ArTfm|Tg(TSPY)9Jshm ArTfm/Y,Tg(TSPY)9Jshm/0
involves: NMRI * STOCK Eda Atp7a
MGI:3775643  MGI:88064  MP:0006308 enlarged seminiferous tubules PMID: 18401008 
ArTfm ArTfm/Y
involves: NMRI * STOCK Eda Atp7a
MGI:88064  MP:0006308 enlarged seminiferous tubules PMID: 18401008 
Artm1.1Chc|Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Artm1.1Chc,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0000709 enlarged thymus PMID: 14676301 
ArTfm-Jms ArTfm-Jms/ArTfm-Jms
C57BL/6JJms
MGI:88064  MP:0001926 female infertility PMID: 7967466 
Artm1Jdz|Tg(Pbsn-cre)20Fwan Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
involves: C57BL/6J * FVB/N
MGI:3717411  MGI:88064  MP:0009243 hairpin sperm flagellum PMID: 18356274 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0001559 hyperglycemia PMID: 15919793 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0003124 hypospadia PMID: 12370412 
Artm1Jdz|Tg(Pbsn-cre)20Fwan Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
involves: C57BL/6J * FVB/N
MGI:3717411  MGI:88064  MP:0000242 impaired fertilization PMID: 18356274 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0005293 impaired glucose tolerance PMID: 15919793 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0003157 impaired muscle relaxation PMID: 16981011 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0005565 increased blood urea nitrogen level PMID: 16981011 
Artm3(AR)Dmr Artm3(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0001260 increased body weight PMID: 16601069 
Artm1(AR)Dmr Artm1(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0001260 increased body weight PMID: 16601069 
ArTfm-Jms ArTfm-Jms/ArTfm-Jms
C57BL/6JJms
MGI:88064  MP:0001260 increased body weight PMID: 7967466 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0005553 increased circulating creatinine level PMID: 16981011 
Artm1Verh|Tg(AMH-cre)1Flor Artm1Verh/Y,Tg(AMH-cre)1Flor/0
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:2450303  MGI:88064  MP:0001750 increased circulating follicle stimulating hormone level PMID: 14745012 
Artm1Reb Artm1Reb/Y
involves: 129S4/SvJaeSor
MGI:88064  MP:0001750 increased circulating follicle stimulating hormone level PMID: 14701682 
Artm1Reb|Tg(Amh-cre)8815Reb Artm1Reb/Y,Tg(Amh-cre)8815Reb/?
involves: 129S4/SvJaeSor * FVB/N
MGI:3044682  MGI:88064  MP:0001750 increased circulating follicle stimulating hormone level PMID: 14701682 
Artm1Chc|Tg(AMH-cre)1Flor Artm1Chc/Y,Tg(AMH-cre)1Flor/0
involves: 129S/SvEv * C57BL/6 * SJL
MGI:2450303  MGI:88064  MP:0001750 increased circulating follicle stimulating hormone level PMID: 15107499 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0005559 increased circulating glucose level PMID: 15919793 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0002079 increased circulating insulin level PMID: 15919793 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0005669 increased circulating leptin level PMID: 15919793 
Artm1.1Verh Artm1.1Verh/Y
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:88064  MP:0001751 increased circulating luteinizing hormone level PMID: 15919750 
Artm1Reb Artm1Reb/Y
involves: 129S4/SvJaeSor
MGI:88064  MP:0001751 increased circulating luteinizing hormone level PMID: 14701682 
Artm1Reb|Tg(Amh-cre)8815Reb Artm1Reb/Y,Tg(Amh-cre)8815Reb/?
involves: 129S4/SvJaeSor * FVB/N
MGI:3044682  MGI:88064  MP:0001751 increased circulating luteinizing hormone level PMID: 14701682 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0001751 increased circulating luteinizing hormone level PMID: 16400023 
Artm1Chc|Tg(AMH-cre)1Flor Artm1Chc/Y,Tg(AMH-cre)1Flor/0
involves: 129S/SvEv * C57BL/6 * SJL
MGI:2450303  MGI:88064  MP:0001751 increased circulating luteinizing hormone level PMID: 15107499 
Artm1.1Chc Artm1.1Chc/Y
involves: 129S/SvEv * C57BL/6 * FVB/N
MGI:88064  MP:0001751 increased circulating luteinizing hormone level PMID: 15107499 
Artm1Reb Artm1Reb/Y
involves: 129S4/SvJaeSor
MGI:88064  MP:0005117 increased circulating pituitary hormone level PMID: 14701682 
Artm1Reb|Tg(Amh-cre)8815Reb Artm1Reb/Y,Tg(Amh-cre)8815Reb/?
involves: 129S4/SvJaeSor * FVB/N
MGI:3044682  MGI:88064  MP:0005117 increased circulating pituitary hormone level PMID: 14701682 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0005627 increased circulating potassium level PMID: 16981011 
Artm1Reb Artm1Reb/Y
involves: 129S4/SvJaeSor
MGI:88064  MP:0002781 increased circulating testosterone level PMID: 14701682 
Artm1Reb|Tg(Amh-cre)8815Reb Artm1Reb/Y,Tg(Amh-cre)8815Reb/?
involves: 129S4/SvJaeSor * FVB/N
MGI:3044682  MGI:88064  MP:0002781 increased circulating testosterone level PMID: 14701682 
Ar+|Artm4(AR)Dmr Artm4(AR)Dmr/Ar+
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0002781 increased circulating testosterone level PMID: 16981011 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0001552 increased circulating triglyceride level PMID: 15919793 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0009285 increased gonadal fat pad weight PMID: 15919793 
ArTfm ArTfm/Y
involves: STOCK Eda Atp7a
MGI:88064  MP:0008214 increased immature B cell number PMID: 9647203 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0009355 increased liver triglyceride level PMID: 15919793 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0004984 increased osteoclast cell number PMID: 12370412 
Artm3(AR)Dmr Artm3(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0005458 increased percent body fat PMID: 16601069 
Artm1(AR)Dmr Artm1(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0005458 increased percent body fat PMID: 16601069 
Artm1(AR)Dmr|Tg(TRAMP)8247Ng Artm1(AR)Dmr/Y,Tg(TRAMP)8247Ng/0
involves: 129S1/Sv * C57BL/6
MGI:2680364  MGI:88064  MP:0010357 increased prostate gland tumor incidence PMID: 16601069 
Artm2(AR)Dmr|Tg(TRAMP)8247Ng Artm2(AR)Dmr/Y,Tg(TRAMP)8247Ng/0
involves: 129S1/Sv * C57BL/6
MGI:2680364  MGI:88064  MP:0010357 increased prostate gland tumor incidence PMID: 16601069 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0009302 increased renal fat pad weight PMID: 15919793 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0005455 increased susceptibility to weight gain PMID: 15919793 
ArTfm|Tg(TSPY)9Jshm ArTfm/Y,Tg(TSPY)9Jshm/0
involves: NMRI * STOCK Eda Atp7a
MGI:3775643  MGI:88064  MP:0004851 increased testis weight PMID: 18401008 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0005317 increased triglyceride level PMID: 15919793 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0009403 increased variability of skeletal muscle fiber size PMID: 16981011 
Artm1Ska|Tg(CMV-cre)1Ipc Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
involves: C57BL/6 * CBA
MGI:2177164  MGI:88064  MP:0000008 increased white adipose tissue amount PMID: 12943692 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0000008 increased white adipose tissue amount PMID: 15919793 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0005331 insulin resistance PMID: 15919793 
Artm1Jdz|Tg(Pbsn-cre)20Fwan Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
involves: C57BL/6J * FVB/N
MGI:3717411  MGI:88064  MP:0009237 kinked sperm flagellum PMID: 18356274 
ArTfm|Tg(TSPY)9Jshm ArTfm/Y,Tg(TSPY)9Jshm/0
involves: NMRI * STOCK Eda Atp7a
MGI:3775643  MGI:88064  MP:0001152 Leydig cell hyperplasia PMID: 18401008 
ArTfm ArTfm/Y
involves: NMRI * STOCK Eda Atp7a
MGI:88064  MP:0001152 Leydig cell hyperplasia PMID: 18401008 
Artm1.1Verh Artm1.1Verh/Y
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:88064  MP:0005536 Leydig cell hypoplasia PMID: 15919750 
Artm1Verh|Tg(AMH-cre)1Flor Artm1Verh/Y,Tg(AMH-cre)1Flor/0
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:2450303  MGI:88064  MP:0005536 Leydig cell hypoplasia PMID: 15919750 
Artm1.1Verh Artm1.1Verh/Y
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:88064  MP:0008280 male germ cell apoptosis PMID: 14745012 
Artm1Verh|Tg(AMH-cre)1Flor Artm1Verh/Y,Tg(AMH-cre)1Flor/0
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:2450303  MGI:88064  MP:0008280 male germ cell apoptosis PMID: 14745012 
Artm1Chc|Tg(AMH-cre)1Flor Artm1Chc/Y,Tg(AMH-cre)1Flor/0
involves: 129S/SvEv * C57BL/6 * SJL
MGI:2450303  MGI:88064  MP:0001925 male infertility PMID: 15107499  17142319 
Amhr2+|Amhr2tm3(cre)Bhr|Artm1Chc Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y
involves: 129S/SvEv * C57BL/6
MGI:105062  MGI:88064  MP:0001925 male infertility PMID: 17142319 
Artm1Jdz|Tg(Abpa-cre)1Cmal Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/0
involves: 129X1/SvJ * C57BL/6 * DBA/2
MGI:4431034  MGI:88064  MP:0001925 male infertility PMID: 19574395 
Artm1Jdz|Tg(AMH-cre)1Flor Artm1Jdz/Y,Tg(AMH-cre)1Flor/0
involves: 129X1/SvJ * C57BL/6 * SJL
MGI:2450303  MGI:88064  MP:0001925 male infertility PMID: 19574395 
Amhtm1Bhr|ArTfm Amhtm1Bhr/Amhtm1Bhr,ArTfm/Y
either: (involves 129P3/J * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6)
MGI:88006  MGI:88064  MP:0002789 male pseudohermaphroditism PMID: 7954809 
ArTfm|Insl3tm1Imad ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad
involves: 129/Sv * CD-1 * STOCK Eda
MGI:108427  MGI:88064  MP:0002789 male pseudohermaphroditism PMID: 10319319 
ArTfm ArTfm/Y
STOCK Eda Atp7a/+ +
MGI:88064  MP:0002789 male pseudohermaphroditism PMID: 5452809 
Artm1.1Reb Artm1.1Reb/Y
involves: 129S4/SvJaeSor * C57BL/6 * DBA/2J
MGI:88064  MP:0002789 male pseudohermaphroditism PMID: 14701682 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0000938 motor neuron degeneration PMID: 16981011 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0000747 muscle weakness PMID: 16981011 
Ar+|Artm4(AR)Dmr Artm4(AR)Dmr/Ar+
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0000747 muscle weakness PMID: 16981011 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0000751 myopathy PMID: 16981011 
Artm1Fcl Artm1Fcl/Artm1Fcl
involves: 129S2/SvPas * C57BL/6
MGI:88064  MP:0002169 no abnormal phenotype detected PMID: 17360365 
Artm1Jdz Artm1Jdz/Y
B6.129X1-Ar
MGI:88064  MP:0002169 no abnormal phenotype detected PMID: 16326839 
Artm1Chc Artm1Chc/Y
involves: 129S/SvEv * C57BL/6J
MGI:88064  MP:0002169 no abnormal phenotype detected PMID: 12370412 
Artm1Rax Artm1Rax/Artm1Rax
involves: 129S/SvEv * C57BL/6J
MGI:88064  MP:0002169 no abnormal phenotype detected PMID: 15294140 
Artm1Rax Artm1Rax/Y
involves: 129S/SvEv * C57BL/6J
MGI:88064  MP:0002169 no abnormal phenotype detected PMID: 15294140 
Artm1Ska|Tg(CMV-cre)1Ipc Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
involves: C57BL/6 * CBA
MGI:2177164  MGI:88064  MP:0001261 obese PMID: 12943692 
Artm1Reb Artm1Reb/Y
involves: 129S4/SvJaeSor
MGI:88064  MP:0002687 oligozoospermia PMID: 14701682 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0002687 oligozoospermia PMID: 16400023 
Artm1Ska|Tg(CMV-cre)1Ipc Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
involves: C57BL/6 * CBA
MGI:2177164  MGI:88064  MP:0001732 postnatal growth retardation PMID: 12943692 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0002083 premature death PMID: 16981011 
Artm1.1Chc Artm1.1Chc/Y
involves: 129S/SvEv * C57BL/6 * FVB/N
MGI:88064  MP:0002009 preneoplasia PMID: 17406000 
Artm1.1Chc Artm1.1Chc/Artm1.1Chc
involves: 129S/SvEv * C57BL/6 * FVB/N
MGI:88064  MP:0002009 preneoplasia PMID: 17406000 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0000748 progressive muscle weakness PMID: 16981011 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0001922 reduced male fertility PMID: 16400023  16981011 
Artm1Fcl Artm1Fcl/Y
involves: 129S2/SvPas * C57BL/6
MGI:88064  MP:0001922 reduced male fertility PMID: 17360365 
Artm1Jdz|Tg(Pbsn-cre)20Fwan Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
involves: C57BL/6J * FVB/N
MGI:3717411  MGI:88064  MP:0001922 reduced male fertility PMID: 18356274 
Amhtm1Bhr|ArTfm Amhtm1Bhr/Amhtm1Bhr,ArTfm/Y
either: (involves 129P3/J * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6)
MGI:88006  MGI:88064  MP:0001939 secondary sex reversal PMID: 7954809 
ArTfm ArTfm/Y
STOCK Eda Atp7a/+ +
MGI:88064  MP:0001939 secondary sex reversal PMID: 5452809 
ArTfm ArTfm/Y
involves: STOCK Eda Atp7a
MGI:88064  MP:0001939 secondary sex reversal PMID: 18401008 
Artm1Ska|Tg(CMV-cre)1Ipc Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
involves: C57BL/6 * CBA
MGI:2177164  MGI:88064  MP:0001939 secondary sex reversal PMID: 12943692 
Artm1.1Verh Artm1.1Verh/Y
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:88064  MP:0001939 secondary sex reversal PMID: 14745012 
Artm1.1Reb Artm1.1Reb/Y
involves: 129S4/SvJaeSor * C57BL/6 * DBA/2J
MGI:88064  MP:0001939 secondary sex reversal PMID: 14701682 
Artm1.1Jdz Artm1.1Jdz/Y
B6.129X1-Ar
MGI:88064  MP:0001939 secondary sex reversal PMID: 16326839 
ArTfm|Tg(TSPY)9Jshm ArTfm/Y,Tg(TSPY)9Jshm/0
involves: NMRI * STOCK Eda Atp7a
MGI:3775643  MGI:88064  MP:0001939 secondary sex reversal PMID: 18401008 
ArTfm ArTfm/Y
involves: NMRI * STOCK Eda Atp7a
MGI:88064  MP:0001939 secondary sex reversal PMID: 18401008 
ArTfm-Jms ArTfm-Jms/Y
C57BL/6JJms
MGI:88064  MP:0001939 secondary sex reversal PMID: 7967466 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0001154 seminiferous tubule degeneration PMID: 17142319 
Artm1Fcl Artm1Fcl/Y
involves: 129S2/SvPas * C57BL/6
MGI:88064  MP:0005250 Sertoli cell hypoplasia PMID: 17360365 
Artm1.1Jdz Artm1.1Jdz/Y
involves: 129X1/SvJ * C57BL/6
MGI:88064  MP:0003550 short perineum PMID: 17317769 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0009413 skeletal muscle fiber atrophy PMID: 16981011 
Artm1Ska|Tg(CMV-cre)1Ipc Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
involves: C57BL/6 * CBA
MGI:2177164  MGI:88064  MP:0002188 small heart PMID: 15961403 
Artm1Ska|Tg(CMV-cre)1Ipc Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
involves: C57BL/6 * CBA
MGI:2177164  MGI:88064  MP:0004565 small myocardial fiber PMID: 15961403 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0005188 small penis PMID: 12370412 
Artm1Jdz|Tg(Pbsn-cre)20Fwan Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
involves: 129X1/SvJ * C57BL/6 * FVB/N
MGI:3717411  MGI:88064  MP:0002774 small prostate gland PMID: 17317769 
Artm1Jdz|Tg(Pbsn-cre)20Fwan Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
involves: 129X1/SvJ * C57BL/6 * FVB/N
MGI:3717411  MGI:88064  MP:0000664 small prostate gland anterior lobe PMID: 17317769 
Artm1Jdz|Tg(Pbsn-cre)20Fwan Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
involves: 129X1/SvJ * C57BL/6 * FVB/N
MGI:3717411  MGI:88064  MP:0000661 small prostate gland ventral lobe PMID: 17317769 
Artm1Jdz|Tg(Pbsn-cre)20Fwan Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
involves: C57BL/6J * FVB/N
MGI:3717411  MGI:88064  MP:0001157 small seminal vesicle PMID: 18356274 
Artm1.1Verh Artm1.1Verh/Y
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:88064  MP:0001153 small seminiferous tubules PMID: 14745012 
Artm1Verh|Tg(AMH-cre)1Flor Artm1Verh/Y,Tg(AMH-cre)1Flor/0
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:2450303  MGI:88064  MP:0001153 small seminiferous tubules PMID: 14745012 
Artm1Fcl Artm1Fcl/Y
involves: 129S2/SvPas * C57BL/6
MGI:88064  MP:0001153 small seminiferous tubules PMID: 17360365 
Artm1.1Jdz Artm1.1Jdz/Y
B6.129X1-Ar
MGI:88064  MP:0001153 small seminiferous tubules PMID: 16326839 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0001153 small seminiferous tubules PMID: 17142319 
Amhr2+|Amhr2tm3(cre)Bhr|Artm1Chc Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y
involves: 129S/SvEv * C57BL/6
MGI:105062  MGI:88064  MP:0001153 small seminiferous tubules PMID: 17142319 
Artm1Jdz|Tg(Abpa-cre)1Cmal Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/0
involves: 129X1/SvJ * C57BL/6 * DBA/2
MGI:4431034  MGI:88064  MP:0001153 small seminiferous tubules PMID: 19574395 
Artm1Jdz|Tg(Abpa-cre)1Cmal Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/Tg(Abpa-cre)1Cmal
involves: 129X1/SvJ * C57BL/6 * DBA/2
MGI:4431034  MGI:88064  MP:0001153 small seminiferous tubules PMID: 19574395 
Artm1Jdz|Tg(AMH-cre)1Flor Artm1Jdz/Y,Tg(AMH-cre)1Flor/0
involves: 129X1/SvJ * C57BL/6 * SJL
MGI:2450303  MGI:88064  MP:0001153 small seminiferous tubules PMID: 19574395 
Artm1Jdz|Tg(AMH-cre)1Flor Artm1Jdz/Y,Tg(AMH-cre)1Flor/Tg(AMH-cre)1Flor
involves: 129X1/SvJ * C57BL/6 * SJL
MGI:2450303  MGI:88064  MP:0001153 small seminiferous tubules PMID: 19574395 
ArTfm ArTfm/Y
STOCK Eda Atp7a/+ +
MGI:88064  MP:0001147 small testis PMID: 5452809 
Artm1.1Verh Artm1.1Verh/Y
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:88064  MP:0001147 small testis PMID: 14745012 
Artm1Verh|Tg(AMH-cre)1Flor Artm1Verh/Y,Tg(AMH-cre)1Flor/0
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
MGI:2450303  MGI:88064  MP:0001147 small testis PMID: 14745012 
Artm1.1Reb Artm1.1Reb/Y
involves: 129S4/SvJaeSor * C57BL/6 * DBA/2J
MGI:88064  MP:0001147 small testis PMID: 14701682 
Artm1.1Jdz Artm1.1Jdz/Y
B6.129X1-Ar
MGI:88064  MP:0001147 small testis PMID: 16326839 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0001147 small testis PMID: 17142319 
Artm1Chc|Tg(AMH-cre)1Flor Artm1Chc/Y,Tg(AMH-cre)1Flor/0
involves: 129S/SvEv * C57BL/6 * SJL
MGI:2450303  MGI:88064  MP:0001147 small testis PMID: 17142319 
Artm1.1Chc Artm1.1Chc/Y
involves: 129S/SvEv * C57BL/6 * FVB/N
MGI:88064  MP:0001147 small testis PMID: 15107499 
Amhr2+|Amhr2tm3(cre)Bhr|Artm1Chc Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y
involves: 129S/SvEv * C57BL/6
MGI:105062  MGI:88064  MP:0001147 small testis PMID: 17142319 
ArTfm-Jms ArTfm-Jms/Y
C57BL/6JJms
MGI:88064  MP:0001147 small testis PMID: 7967466 
Artm1Ska|Tg(CMV-cre)1Ipc Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
involves: C57BL/6 * CBA
MGI:2177164  MGI:88064  MP:0003205 testicular atrophy PMID: 12943692 
Artm4(AR)Dmr Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J
MGI:88064  MP:0003205 testicular atrophy PMID: 16400023  16981011 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0003205 testicular atrophy PMID: 15919793 
Artm1Chc|Tg(ACTB-cre)2Mrt Artm1Chc/Y,Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N
MGI:2176049  MGI:88064  MP:0001940 testicular hypoplasia PMID: 12370412 
ArTfm|Tg(TSPY)9Jshm ArTfm/Y,Tg(TSPY)9Jshm/0
involves: NMRI * STOCK Eda Atp7a
MGI:3775643  MGI:88064  MP:0006262 testis tumor PMID: 18401008 
ArTfm ArTfm/Y
involves: NMRI * STOCK Eda Atp7a
MGI:88064  MP:0006262 testis tumor PMID: 18401008 
Artm1Ska|Tg(CMV-cre)1Ipc Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
involves: C57BL/6 * CBA
MGI:2177164  MGI:88064  MP:0000280 thin ventricular wall PMID: 15961403 
ArTfm ArTfm/Y
STOCK Eda Atp7a/+ +
MGI:88064  MP:0001144 vagina atresia PMID: 5452809 
Clinically-Relevant Mutations and Pathophysiology
Disease:  Prostate cancer
OMIM:  176807
Comments: 
References:  35
Mutations not determined
Disease:  Klinefelter's syndrome (47, XXY - hypogonadism)
OMIM:  400045
Comments: 
References:  24,29