Nomenclature: K2P18.1

Family: Two-P potassium channels

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation. 

Contents

Gene and Protein Information
Species TM P Loops AA Chromosomal Location Gene Symbol Gene Name Reference
Human 4 0 384 10q25.3 KCNK18 potassium channel, subfamily K, member 18 1
Mouse 4 0 394 19 D3 Kcnk18 potassium channel, subfamily K, member 18
Rat 4 0 405 1q55 Kcnk18 potassium channel, subfamily K, member 18
Previous and Unofficial Names
KCNK18
TRESK-1/TRESK-2
K2P18.1
TRESK-2
TRESK2
TRESK
TRIK
TWIK related spinal cord K+ channel
potassium channel subfamily K member 18
potassium channel, subfamily K, member 18
tandem-pore K+ (K(2P)) channel
two-pore-domain potassium channel TRESK
LOC332396
Gm781
Database Links
Ensembl Gene
Entrez Gene
GeneCards
GenitoUrinary Development Molecular Anatomy Project
HomoloGene
Human Protein Reference Database
InterPro
KEGG Gene
OMIM
PharmGKB Gene
PhosphoSitePlus
Protein Ontology (PRO)
RefSeq Nucleotide
RefSeq Protein
TreeFam
UniGene Hs.
UniProtKB
Wikipedia
Functional Characteristics
Background current
Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Concentration range (M) Holding voltage (mV) Reference
arachidonic acid Hs - - - - -

REFERENCES

1. Sano Y, Inamura K, Miyake A, Mochizuki S, Kitada C, Yokoi H, Nozawa K, Okada H, Matsushime H, Furuichi K. (2003) A novel two-pore domain K+ channel, TRESK, is localized in the spinal cord. J. Biol. Chem.278 (30): 27406-12. [PMID:12754259]

To cite this database page, please use the following:

Leigh Daniel Plant, Douglas A. Bayliss, Donghee Kim, Florian Lesage, Steve A.N. Goldstein.
Two-P potassium channels: K2P18.1. Last modified on 25/03/2014. Accessed on 01/10/2014. IUPHAR database (IUPHAR-DB), http://www.iuphar-db.org/DATABASE/ObjectDisplayForward?objectId=527.

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