Nomenclature: K2P12.1

Family: Two-P potassium channels

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation. 

Contents

Gene and Protein Information
Species TM P Loops AA Chromosomal Location Gene Symbol Gene Name Reference
Human 4 0 430 2p22-p21 KCNK12 potassium channel, subfamily K, member 12 1
Mouse 4 0 430 17 E4 Kcnk12 potassium channel, subfamily K, member 12
Rat 4 0 430 6q12 Kcnk12 potassium channel, subfamily K, member 12
Previous and Unofficial Names
KCNK12
THIK-2
K2P12.1
THIK2
potassium channel subfamily K member 12
potassium channel, subfamily K, member 12
tandem pore domain halothane-inhibited potassium channel 2
tandem pore domain potassium channel THIK-2
mntk1
Database Links
Ensembl Gene
Entrez Gene
GeneCards
GenitoUrinary Development Molecular Anatomy Project
HomoloGene
Human Protein Reference Database
InterPro
KEGG Gene
OMIM
PharmGKB Gene
PhosphoSitePlus
Protein Ontology (PRO)
RefSeq Nucleotide
RefSeq Protein
TreeFam
UniGene Hs.
UniProtKB
Wikipedia
Functional Characteristics
Background current
Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Concentration range (M) Holding voltage (mV) Reference
halothane Hs - - - - -

REFERENCES

1. Rajan S, Wischmeyer E, Karschin C, Preisig-Müller R, Grzeschik KH, Daut J, Karschin A, Derst C. (2001) THIK-1 and THIK-2, a novel subfamily of tandem pore domain K+ channels. J. Biol. Chem.276 (10): 7302-11. [PMID:11060316]

To cite this database page, please use the following:

Leigh Daniel Plant, Douglas A. Bayliss, Donghee Kim, Florian Lesage, Steve A.N. Goldstein.
Two-P potassium channels: K2P12.1. Last modified on 11/02/2014. Accessed on 23/09/2014. IUPHAR database (IUPHAR-DB), http://www.iuphar-db.org/DATABASE/ObjectDisplayForward?objectId=522.

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