Nomenclature: K2P7.1

Family: Two-P potassium channels

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation. 

Contents

Gene and Protein Information
Species TM P Loops AA Chromosomal Location Gene Symbol Gene Name Reference
Human 4 0 307 11q13 KCNK7 potassium channel, subfamily K, member 7 2
Mouse 4 0 343 19 B2 Kcnk7 potassium channel, subfamily K, member 7 1-2
Rat 4 0 311 1q43 Kcnk7 potassium channel, subfamily K, member 7
Previous and Unofficial Names
KCNK7
kcnk8
K2P7.1
LOC499303
RGD1565025_predicted
similar to two pore domain K+ channel subunit
similar to two pore domain K+ channel subunit (predicted)
Knot
Mlk3
2310014G03Rik
Database Links
Ensembl Gene
Entrez Gene
GeneCards
GenitoUrinary Development Molecular Anatomy Project
HomoloGene
Human Protein Reference Database
InterPro
KEGG Gene
OMIM
PharmGKB Gene
Protein Ontology (PRO)
RefSeq Nucleotide
RefSeq Protein
TreeFam
UniGene Hs.
UniProtKB
Wikipedia
Functional Characteristics
Background current
Phenotypes, Alleles and Disease Models Mouse data from MGI

Show »

Allele Composition & genetic background Accession Phenotype Id Phenotype Reference
Kcnk7tm1Dgen Kcnk7tm1Dgen/Kcnk7tm1Dgen
involves: 129P2/OlaHsd * C57BL/6
MGI:1341841  MP:0002169 no abnormal phenotype detected PMID: 18572259 

REFERENCES

1. Bockenhauer D, Nimmakayalu MA, Ward DC, Goldstein SA, Gallagher PG. (2000) Genomic organization and chromosomal localization of the murine 2 P domain potassium channel gene Kcnk8: conservation of gene structure in 2 P domain potassium channels. Gene261 (2): 365-72. [PMID:11167025]

2. Salinas M, Reyes R, Lesage F, Fosset M, Heurteaux C, Romey G, Lazdunski M. (1999) Cloning of a new mouse two-P domain channel subunit and a human homologue with a unique pore structure. J. Biol. Chem.274 (17): 11751-60. [PMID:10206991]

To cite this database page, please use the following:

Leigh Daniel Plant, Douglas A. Bayliss, Donghee Kim, Florian Lesage, Steve A.N. Goldstein.
Two-P potassium channels: K2P7.1. Last modified on 31/01/2014. Accessed on 24/10/2014. IUPHAR database (IUPHAR-DB), http://www.iuphar-db.org/DATABASE/ObjectDisplayForward?objectId=519.

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