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GPR125
Family: Class B Orphans
| Gene and Protein Information |
|
class B G protein-coupled receptor |
| Species |
TM |
AA |
Chromosomal Location |
Gene Symbol |
Gene Name |
Reference |
| Human |
7 |
1321 |
4p15.31 |
GPR125
|
G protein-coupled receptor 125
|
1 |
| Mouse |
7 |
1449 |
5 B3 |
Gpr125
|
G protein-coupled receptor 125
|
|
| Rat |
7 |
1455 |
14q11 |
Gpr125
|
G protein-coupled receptor 125
|
|
| Previous and Unofficial Names |
| FLJ38547 |
| PGR21 |
| TEM5-like |
| TEM5L |
| Gpr125_predicted |
| LOC305408 |
| G protein-coupled receptor 125 |
| G protein-coupled receptor 125 (predicted) |
| probable G-protein coupled receptor 125 |
| 3830613O22Rik |
| AU044632 |
| Database Links |
|
Ensembl
|
ENSG00000152990 (Hs), ENSMUSG00000029090 (Mm)
|
|
Entrez Gene
|
166647 (Hs), 70693 (Mm), 305408 (Rn)
|
|
GeneCards
|
GPR125 (Hs)
|
|
GenitoUrinary Development Molecular Anatomy Project
|
Gpr125 (Mm)
|
|
HomoloGene
|
19235 (Hs)
|
|
Human Protein Reference Database
|
11011 (Hs)
|
|
InterPro
|
Q8IWK6 (Hs), Q7TT36 (Mm)
|
|
KEGG Gene
|
hsa:166647 (Hs), mmu:70693 (Mm), rno:305408 (Rn)
|
|
PharmGKB Gene
|
PA134919579 (Hs)
|
|
PhosphoSitePlus
|
Q8IWK6 (Hs), Q7TT36 (Mm)
|
|
RefSeq Nucleotide
|
NM_145290 (Hs), NM_133911 (Mm)
|
|
RefSeq Protein
|
NP_660333 (Hs), NP_598672 (Mm)
|
|
TreeFam
|
ENSG00000152990 (Hs), ENSMUSG00000029090 (Mm)
|
|
UniGene Hs.
|
99195 (Hs)
|
|
UniProt
|
Q8IWK6 (Hs), Q7TT36 (Mm)
|
|
Wikipedia
|
GPR125
|
|
Orphan and other 7TM receptors
|
| Agonist Comments |
| No ligands identified: orphan receptor. |
| Tissue Distribution
|
| Skeletal muscle, prostate, testis, colon >> heart, placenta, pancreas, small intestine > brain, spleen, thymus. Not detected in lung or white blood cells. |
| Species: |
Human |
| Technique: |
Northern blotting. |
| References: |
1 |
|
|
| Expression Datasets |
|
Click here to show/hide data
Log average relative transcript abundance in mouse tissues measured by qPCR from Regard, J.B., Sato, I.T., and Coughlin, S.R. (2008). Anatomical profiling of G protein-coupled receptor expression. Cell, 135(3): 561-71. [PMID:18984166] [Raw data: website]
There should be a chart of expression data here, you may need to enable JavaScript!
|
|
REFERENCES
Show »« Hide
1. Yamamoto, Y., Irie, K., Asada, M., Mino, A., Mandai, K. and Takai, Y. (2004) Direct binding of the human homologue of the Drosophila disc large tumor suppressor gene to seven-pass transmembrane proteins, tumor endothelial marker 5 (TEM5), and a novel TEM5-like protein.
Oncogene, 23: 3889-3897.
[PMID:15021905]
To cite this database page, please use the following:
Tom I. Bonner.
Class B Orphans: GPR125. Last modified on 13/02/2013. Accessed on 22/05/2013. IUPHAR database (IUPHAR-DB), http://www.iuphar-db.org/DATABASE/ObjectDisplayForward?objectId=199.
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