Nomenclature: GPR173

Family: Class A Orphans

Annotation status:  image of a green circle Annotated and expert reviewed. Please contact us if you can help with updates. 


Gene and Protein Information
class A G protein-coupled receptor
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 7 373 Xp11 GPR173 G protein-coupled receptor 173
Mouse 7 373 X F2 Gpr173 G-protein coupled receptor 173
Rat 7 373 Xq21 Gpr173 G-protein coupled receptor 173
Previous and Unofficial Names
Super conserved receptor expressed in brain 3
G-protein coupled receptor 173
probable G-protein coupled receptor 173
G protein coupled receptor 173
Database Links
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Reference Database
PharmGKB Gene
Protein Ontology (PRO)
RefSeq Nucleotide
RefSeq Protein
UniGene Hs.
Tissue Distribution
Brain, ovary, small intestine
Species:  Human
Technique:  Northern blot
References:  1
Expression Datasets

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Log average relative transcript abundance in mouse tissues measured by qPCR from Regard, J.B., Sato, I.T., and Coughlin, S.R. (2008). Anatomical profiling of G protein-coupled receptor expression. Cell, 135(3): 561-71. [PMID:18984166] [Raw data: website]

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Available Assays
DiscoveRx PathHunter® CHO-K1 GPR173 β-Arrestin Orphan GPCR Cell Line (Cat no. 93-0380C2A)
PathHunter® eXpress GPR173 CHO-K1 β-Arrestin Orphan GPCR Assay (Cat no. 93-0380E2ACP1M)
PathHunter® HEK 293 GPR173 β-Arrestin Orphan GPCR Cell Line (Cat no. 93-0380C1A)
more info


1. Matsumoto M, Saito T, Takasaki J, Kamohara M, Sugimoto T, Kobayashi M, Tadokoro M, Matsumoto S, Ohishi T, Furuichi K. (2000) An evolutionarily conserved G-protein coupled receptor family, SREB, expressed in the central nervous system. Biochem. Biophys. Res. Commun.272 (2): 576-82. [PMID:10833454]

To cite this database page, please use the following:

Anthony P. Davenport, Stephen Alexander, Joanna L. Sharman, Adam J. Pawson, Helen E. Benson, Amy E. Monaghan, Wen Chiy Liew, Chido Mpamhanga, Jim Battey, Richard V. Benya, Robert T. Jensen, Sadashiva Karnik, Evi Kostenis, Eliot Spindel, Laura Storjohann, Kalyan Tirupula, Tom I. Bonner, Richard Neubig, Jean-Philippe Pin, Michael Spedding, Anthony Harmar.
Class A Orphans: GPR173. Last modified on 02/07/2013. Accessed on 24/10/2014. IUPHAR database (IUPHAR-DB),

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