Nomenclature: GPR141

Family: Class A Orphans

Annotation status:  image of a green circle Annotated and expert reviewed. Please contact us if you can help with updates. 


Gene and Protein Information
class A G protein-coupled receptor
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 7 305 7p14.1 GPR141 G protein-coupled receptor 141
Mouse 7 305 13 A2 Gpr141 G protein-coupled receptor 141
Rat 7 247 17q12.1 Gpr141 G protein-coupled receptor 141
Previous and Unofficial Names
G-protein coupled receptor 141
G-protein coupled receptor PGR13
probable G-protein coupled receptor 141
G protein-coupled receptor 141
Database Links
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Reference Database
PharmGKB Gene
Protein Ontology (PRO)
RefSeq Nucleotide
RefSeq Protein
UniGene Hs.
Tissue Distribution
Marrow, cancer cells such as human fibrosarcoma HT1080 cells
Species:  Human
Technique:  Expressed sequence tag
References:  1
Expression Datasets

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Log average relative transcript abundance in mouse tissues measured by qPCR from Regard, J.B., Sato, I.T., and Coughlin, S.R. (2008). Anatomical profiling of G protein-coupled receptor expression. Cell, 135(3): 561-71. [PMID:18984166] [Raw data: website]

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Available Assays
DiscoveRx PathHunter® CHO-K1 GPR141 β-Arrestin Orphan GPCR Cell Line (Cat no. 93-0385C2A)
PathHunter® eXpress GPR141 CHO-K1 β-Arrestin Orphan GPCR Assay (Cat no. 93-0385E2ACP1M)
more info


1. Fredriksson R, Höglund PJ, Gloriam DE, Lagerström MC, Schiöth HB. (2003) Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives. FEBS Lett.554 (3): 381-8. [PMID:14623098]

To cite this database page, please use the following:

Anthony P. Davenport, Stephen Alexander, Joanna L. Sharman, Adam J. Pawson, Helen E. Benson, Amy E. Monaghan, Wen Chiy Liew, Chido Mpamhanga, Jim Battey, Richard V. Benya, Robert T. Jensen, Sadashiva Karnik, Evi Kostenis, Eliot Spindel, Laura Storjohann, Kalyan Tirupula, Tom I. Bonner, Richard Neubig, Jean-Philippe Pin, Michael Spedding, Anthony Harmar.
Class A Orphans: GPR141. Last modified on 02/07/2013. Accessed on 31/10/2014. IUPHAR database (IUPHAR-DB),

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