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ρ3

Family: GABAA receptors

Contents:
Gene and Protein Information
Previous and Unofficial Names
Database Links
References
Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 4 467 3q11.2 GABRR3 gamma-aminobutyric acid (GABA) A receptor, rho 3 1
Mouse 4 464 16 C1.3 Gabrr3 gamma-aminobutyric acid (GABA) receptor, rho 3 3
Rat 4 464 11q12 Gabrr3 gamma-aminobutyric acid (GABA) A receptor, rho 3 2
Previous and Unofficial Names
gamma-aminobutyric acid (GABA) receptor, rho 3
GABA(A) receptor, rho 3
Loc192258
GABA receptor rho-3 subunit
GABA(A) receptor subunit rho-3
GABA(C) receptor
gamma-aminobutyric acid receptor subunit rho-3
Database Links
ChEMBL Target 10345 (Hs), 100015 (Rn)
Ensembl ENSG00000183185 (Hs), ENSMUSG00000074991 (Mm), ENSRNOG00000001679 (Rn)
Entrez Gene 200959 (Hs), 328699 (Mm), 192258 (Rn)
GeneCards GABRR3 (Hs)
GenitoUrinary Development Molecular Anatomy Project Gabrr3 (Mm)
HomoloGene 26716 (Hs)
InterPro A8MPY1 (Hs), P50573 (Rn)
KEGG Gene hsa:200959 (Hs), mmu:328699 (Mm), rno:192258 (Rn)
PharmGKB Gene PA134952133 (Hs)
PhosphoSitePlus A8MPY1 (Hs), Q3URA6 (Mm)
Protein Ontology (PRO) PRO:000007784 (Hs)
RefSeq Nucleotide NM_001105580 (Hs), NM_001081190 (Mm), NM_138897 (Rn)
RefSeq Protein NP_001099050 (Hs), NP_001074659 (Mm), NP_620252 (Rn)
TreeFam ENSG00000183185 (Hs), ENSMUSG00000074991 (Mm), ENSRNOG00000001679 (Rn)
UniGene Hs. 534578 (Hs)
UniProt A8MPY1 (Hs), P50573 (Rn)
Wikipedia ρ3
GABAA receptors
Search for 3D structures on the PDB
Search by keyword: GABAA receptors ρ3 Search by accession number: P50573, A8MPY1
Natural/Endogenous Ligand(s)
GABA

REFERENCES

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1. Bailey, ME; Albrecht, BE; Johnson, KJ; Darlison, MG. (1999) Genetic linkage and radiation hybrid mapping of the three human GABA(C) receptor rho subunit genes: GABRR1, GABRR2 and GABRR3. Biochim. Biophys. Acta, 1447 (2-3): 307-12. [PMID:10542332]

2. Ogurusu, T; Shingai, R. (1996) Cloning of a putative gamma-aminobutyric acid (GABA) receptor subunit rho 3 cDNA. Biochim. Biophys. Acta, 1305 (1-2): 15-8. [PMID:8605242]

3. Rose, M; Dütting, E; Schröder, N; Sticht, H; Brandstätter, JH; Enz, R. (2008) PNUTS forms a trimeric protein complex with GABA(C) receptors and protein phosphatase 1. Mol. Cell. Neurosci., 37 (4): 808-19. [PMID:18325784]

To cite this database page, please use the following:

Richard Olsen, John A. Peters, Tim G. Hales, Werner Sieghart, Uwe Rudolph, Jeremy J. Lambert, Delia Belelli, Bernhard Luscher.
GABAA receptors: ρ3. Last modified on 21/05/2012. Accessed on 19/05/2013. IUPHAR database (IUPHAR-DB), http://www.iuphar-db.org/DATABASE/ObjectDisplayForward?objectId=422.


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