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ρ1

Family: GABAA receptors

Contents:
Gene and Protein Information
Previous and Unofficial Names
Database Links
References
Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 4 473 6q13-q16.3 GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 2
Mouse 4 474 4 A5 Gabrr1 gamma-aminobutyric acid (GABA) C receptor, subunit rho 1 3
Rat 4 474 5q21 Gabrr1 gamma-aminobutyric acid (GABA) A receptor, rho 1 1
Previous and Unofficial Names
gamma-aminobutyric acid (GABA) receptor, rho 1
GABA(A) receptor, rho 1
GABA(A) receptor subunit rho-1
GABA(C) receptor
gamma-aminobutyric acid (GABA-A) receptor subunit rho 1
gamma-aminobutyric acid (GABA-A) receptor, subunit rho 1
gamma-aminobutyric acid (GABA-C) receptor, subunit rho 1
gamma-aminobutyric acid A receptor, rho 1
gamma-aminobutyric acid receptor subunit rho-1
GABA-C
Database Links
ChEMBL Target 13064 (Hs), 13065 (Mm), 11525 (Rn)
DrugBank Target 142 (Hs)
Ensembl ENSG00000146276 (Hs), ENSMUSG00000028280 (Mm), ENSRNOG00000007603 (Rn)
Entrez Gene 2569 (Hs), 14408 (Mm), 29694 (Rn)
GeneCards GABRR1 (Hs)
GenitoUrinary Development Molecular Anatomy Project Gabrr1 (Mm)
HomoloGene 20470 (Hs)
Human Protein Reference Database 15921 (Hs)
InterPro P24046 (Hs), P56475 (Mm), P50572 (Rn)
KEGG Gene hsa:2569 (Hs), mmu:14408 (Mm), rno:29694 (Rn)
OMIM 137161 (Hs)
PharmGKB Gene PA28505 (Hs)
PhosphoSitePlus P24046 (Hs), P56475 (Mm), P50572 (Rn)
Protein Ontology (PRO) PRO:000007782 (Hs)
RefSeq Nucleotide NM_002042 (Hs), NM_008075 (Mm), NM_017291 (Rn)
RefSeq Protein NP_002033 (Hs), NP_032101 (Mm), NP_058987 (Rn)
TreeFam ENSG00000146276 (Hs), ENSMUSG00000028280 (Mm), ENSRNOG00000007603 (Rn)
UniGene Hs. 437745 (Hs)
UniProt P24046 (Hs), P56475 (Mm), P50572 (Rn)
Wikipedia ρ1
GABAA receptors
Search for 3D structures on the PDB
Search by keyword: GABAA receptors ρ1 Search by accession number: P50572, P56475, P24046
Natural/Endogenous Ligand(s)
GABA

REFERENCES

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1. Cutting, GR; Curristin, S; Zoghbi, H; O'Hara, B; Seldin, MF; Uhl, GR. (1992) Identification of a putative gamma-aminobutyric acid (GABA) receptor subunit rho2 cDNA and colocalization of the genes encoding rho2 (GABRR2) and rho1 (GABRR1) to human chromosome 6q14-q21 and mouse chromosome 4. Genomics, 12 (4): 801-6. [PMID:1315307]

2. Cutting, GR; Lu, L; O'Hara, BF; Kasch, LM; Montrose-Rafizadeh, C; Donovan, DM; Shimada, S; Antonarakis, SE; Guggino, WB; Uhl, GR. (1991) Cloning of the gamma-aminobutyric acid (GABA) rho 1 cDNA: a GABA receptor subunit highly expressed in the retina. Proc. Natl. Acad. Sci. U.S.A., 88 (7): 2673-7. [PMID:1849271]

3. Zhang, D; Pan, ZH; Zhang, X; Brideau, AD; Lipton, SA. (1995) Cloning of a gamma-aminobutyric acid type C receptor subunit in rat retina with a methionine residue critical for picrotoxinin channel block. Proc. Natl. Acad. Sci. U.S.A., 92 (25): 11756-60. [PMID:8524843]

To cite this database page, please use the following:

Richard Olsen, John A. Peters, Tim G. Hales, Werner Sieghart, Uwe Rudolph, Jeremy J. Lambert, Delia Belelli, Bernhard Luscher.
GABAA receptors: ρ1. Last modified on 11/10/2012. Accessed on 25/05/2013. IUPHAR database (IUPHAR-DB), http://www.iuphar-db.org/DATABASE/ObjectDisplayForward?objectId=420.


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