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β1

Family: GABAA receptors

Contents:
Gene and Protein Information
Previous and Unofficial Names
Database Links
References
Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 4 474 4p12 GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 2-3
Mouse 4 474 5 C3.2 Gabrb1 gamma-aminobutyric acid (GABA) A receptor, subunit beta 1 1
Rat 4 474 14p11 Gabrb1 gamma-aminobutyric acid (GABA) A receptor, beta 1 4
Previous and Unofficial Names
GABA(A) receptor, beta 1
GARB1
GABA(A) receptor subunit beta-1
Gamma-aminobutyric acid receptor beta 1
gamma-aminobutyric acid (GABA-A) receptor, subunit beta 1
gamma-aminobutyric acid receptor subunit beta-1
gamma-aminobutyric acid receptor, subunit beta 1
Gabrb-1
AW061132
B230208N19Rik
Database Links
ChEMBL Target 11217 (Hs), 11459 (Mm), 13051 (Rn)
DrugBank Target 4098 (Hs)
Ensembl ENSG00000163288 (Hs), ENSMUSG00000029212 (Mm), ENSRNOG00000002327 (Rn)
Entrez Gene 2560 (Hs), 14400 (Mm), 25450 (Rn)
GeneCards GABRB1 (Hs)
GenitoUrinary Development Molecular Anatomy Project Gabrb1 (Mm)
HomoloGene 20221 (Hs)
Human Protein Reference Database 15924 (Hs)
InterPro P18505 (Hs), P50571 (Mm), P15431 (Rn)
KEGG Gene hsa:2560 (Hs), mmu:14400 (Mm), rno:25450 (Rn)
OMIM 137190 (Hs)
PharmGKB Gene PA28495 (Hs)
PhosphoSitePlus P18505 (Hs), P50571 (Mm), P15431 (Rn)
Protein Ontology (PRO) PRO:000007772 (Hs)
RefSeq Nucleotide NM_000812 (Hs), NM_008069 (Mm), NM_012956 (Rn)
RefSeq Protein NP_000803 (Hs), NP_032095 (Mm), NP_037088 (Rn)
TreeFam ENSG00000163288 (Hs), ENSMUSG00000029212 (Mm), ENSRNOG00000002327 (Rn)
UniGene Hs. 27283 (Hs)
UniProt P18505 (Hs), P50571 (Mm), P15431 (Rn)
Wikipedia β1
GABAA receptors
Search for 3D structures on the PDB
Search by keyword: GABAA receptors β1 Search by accession number: P15431, P50571, P18505
Natural/Endogenous Ligand(s)
GABA

REFERENCES

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1. Kamatchi, GL; Kofuji, P; Wang, JB; Fernando, JC; Liu, Z; Mathura, JR; Burt, DR. (1995) GABAA receptor beta 1, beta 2, and beta 3 subunits: comparisons in DBA/2J and C57BL/6J mice. Biochim. Biophys. Acta, 1261 (1): 134-42. [PMID:7893750]

2. Kirkness, EF; Kusiak, JW; Fleming, JT; Menninger, J; Gocayne, JD; Ward, DC; Venter, JC. (1991) Isolation, characterization, and localization of human genomic DNA encoding the beta 1 subunit of the GABAA receptor (GABRB1). Genomics, 10 (4): 985-95. [PMID:1655634]

3. Schofield, PR; Pritchett, DB; Sontheimer, H; Kettenmann, H; Seeburg, PH. (1989) Sequence and expression of human GABAA receptor alpha 1 and beta 1 subunits. FEBS Lett., 244 (2): 361-4. [PMID:2465923]

4. Ymer, S; Schofield, PR; Draguhn, A; Werner, P; Köhler, M; Seeburg, PH. (1989) GABAA receptor beta subunit heterogeneity: functional expression of cloned cDNAs. EMBO J., 8 (6): 1665-70. [PMID:2548852]

To cite this database page, please use the following:

Richard Olsen, John A. Peters, Tim G. Hales, Werner Sieghart, Uwe Rudolph, Jeremy J. Lambert, Delia Belelli, Bernhard Luscher.
GABAA receptors: β1. Last modified on 10/01/2012. Accessed on 20/05/2013. IUPHAR database (IUPHAR-DB), http://www.iuphar-db.org/DATABASE/ObjectDisplayForward?objectId=410.


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