Ligand Id: 725
Ligand name L-ornithine

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 4
Topological polar surface area 89.34
Molecular weight 132.09
XLogP -3.31
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands
References
1. Fiermonte, G; Dolce, V; David, L; Santorelli, FM; Dionisi-Vici, C; Palmieri, F; Walker, JE. (2003)
The mitochondrial ornithine transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution of two human isoforms.
J. Biol. Chem., 278 (35): 32778-83. [PMID:12807890]
2. Wellendorph, P., Hansen, K. B., Balsgaard, A., Greenwood, J. R., Egebjerg, J. and Brauner-Osborne, H. (2005)
Deorphanization of GPRC6A: a promiscuous L-alpha-amino acid receptor with preference for basic amino acids.
Mol Pharmacol., 67: 589-597. [PMID:15576628]

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