Ligand Id: 725
Ligand name L-ornithine

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 4
Topological polar surface area 89.34
Molecular weight 132.09
XLogP -3.31
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands
Enzymes Catalysing Reactions Involving this Compound
Enzyme DB page EC number Reaction Reference
Ornithine decarboxylase
Transporters Moving this Compound Across a Lipid Membrane
Transporter DB page EC number Reaction Reference
Cationic amino acid transporter 3
Mitochondrial ornithine transporter 2 1
High affinity cationic amino acid transporter 1
Mitochondrial ornithine transporter 1 1
Low affinity cationic amino acid transporter 2
Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
GPRC6 receptor Agonist Full agonist 4.0 pEC50 - 2
pEC50 4.0 [2]
Ligand mentioned in the following text fields in the Guide to PHARMACOLOGY

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