Ligand Id: 725
Ligand name L-ornithine

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 4
Topological polar surface area 89.34
Molecular weight 132.09
XLogP -3.31
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands
Enzyme Reactions
Enzyme DB page EC number Reaction Reference
Ornithine decarboxylase View in GRAC
Transporters
Transporter DB page EC number Reaction Reference
Mitochondrial ornithine transporter 2 View in GRAC 1
Cationic amino acid transporter 3 View in GRAC
Mitochondrial ornithine transporter 1 View in GRAC 1
High affinity cationic amino acid transporter 1 View in GRAC
Low affinity cationic amino acid transporter 2 View in GRAC

Selectivity data from IUPHAR-DB

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
GPRC6 receptor Agonist Full agonist 4.0 pEC50 - 2

Please note: The activity data given on this ligand page represents selected literature values and may not include all reported data.
For more details please contact: curators@iuphar-db.org

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