Ligand Id: 296
Ligand name arecoline

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 29.54
Molecular weight 155.09
XLogP 0.17
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands

Selectivity data from IUPHAR-DB

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
M1 receptor Agonist Full agonist 5.7 pKi - 2
M4 receptor Agonist Full agonist 5.5 pKi - 2
M3 receptor Agonist Full agonist 5.4 pKi - 2
M2 receptor Agonist Full agonist 5.2 pKi - 2
Selectivity at rat GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
M1 receptor Agonist Partial agonist 5.3 pKi - 1

Please note: The activity data given on this ligand page represents selected literature values and may not include all reported data.
For more details please contact: curators@iuphar-db.org

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