Ligand Id: 296
Ligand name arecoline

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 29.54
Molecular weight 155.09
XLogP 0.17
No. Lipinski's rules broken 0

Molecular properties generated using the CDK


Summary Biological activity References Structure Similar ligands Suppliers
Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
M1 receptor Agonist Full agonist 5.7 pKi - 1
pKi 5.7 [1]
M4 receptor Agonist Full agonist 5.5 pKi - 1
pKi 5.5 [1]
M3 receptor Agonist Full agonist 5.4 pKi - 1
pKi 5.4 [1]
M2 receptor Agonist Full agonist 5.2 pKi - 1
pKi 5.2 [1]
Selectivity at rat GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
M1 receptor Agonist Partial agonist 5.3 pKi - 2
pKi 5.3 [2]

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