Ligand Id: 555
Ligand name practolol

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 8
Topological polar surface area 70.59
Molecular weight 266.16
XLogP 1.42
No. Lipinski's rules broken 0

Molecular properties generated using the CDK


Summary Biological activity Clinical data References Structure
Classification
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name
N-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide
International Nonproprietary Names
INN number INN
2832 practolol
Synonyms
AY-21011
ICI-50172
practalol
Database Links
BindingDB Ligand 25749
CAS Registry No. 6673-35-4 (source: Scifinder)
ChEBI CHEBI:101380
ChEMBL Ligand CHEMBL6995
DrugBank Ligand DB01297
PharmGKB Drug PA164752820
PubChem CID 4883
Search Google for chemical match using the InChIKey DURULFYMVIFBIR-UHFFFAOYSA-N
Search Google for chemicals with the same backbone DURULFYMVIFBIR
Search PubMed clinical trials practolol
Search PubMed titles practolol
Search PubMed titles/abstracts practolol
Wikipedia Practolol
ZINC ZINC00000652
Comments
The approved drug practolol is mixture of two enantiomers. The structure shown here does not specify stereochemistry and represents the mixture. There is no information regarding approval for medical use of practolol on the US FDA website. Individual national agencies may have granted marketing approval.

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