Ligand Id: 2881
Ligand name levonorgestrel

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 37.3
Molecular weight 312.21
XLogP 3.81
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands
Classification
Compound class Synthetic organic
Approved drug? Yes (source: DrugBank)
IUPAC Name
(8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
Summary of Clinical Use
A contraceptive, also used in the treatment of menstrual disorders and endometriosis, levonorgestrel is the active component of the approved drug norgestrel.
International Nonproprietary Names
INN number INN
3475 levonorgestrel
2157 norgestrel
Synonyms
13β-Ethyl-17α-ethynyl-17β-hydroxygon-4-en-3-one
l-norgestrel
Database Links
CAS Registry No. 797-63-7 (source: Scifinder)
ChEMBL Ligand 428164, 239397
DrugBank Ligand DB00367
PubChem CID 13109
RCSB PDB Ligand NOG
Search on ChemSpider WWYNJERNGUHSAO-XUDSTZEESA-N
Wikipedia Levonorgestrel
ZINC ZINC03814395

Please note: some links may refer to related isomers. For more details please contact: curators@iuphar-db.org

Comments
Levonorgestrel is the name for the active isomer in norgestrel, a racemic mixture

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