Ligand Id: 1728
Ligand name suramin

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 29
Hydrogen bond donors 12
Rotatable bonds 22
Topological polar surface area 534.03
Molecular weight 1296.05
XLogP 1.05
No. Lipinski's rules broken 3

Molecular properties generated using the CDK


Summary Biological activity Clinical data References Structure Similar ligands
Classification
Compound class Synthetic organic
Approved drug? Yes
DrugBank groups approved
IUPAC Name
8-[[4-methyl-3-[[3-[[3-[[2-methyl-5-[(4,6,8-trisulfonaphthalen-1-yl)carbamoyl]phenyl]carbamoyl]phenyl]carbamoylamino]benzoyl]amino]benzoyl]amino]naphthalene-1,3,5-trisulfonic acid
International Nonproprietary Names
INN number INN
2899 suramin sodium
Synonyms
CI-1003
suramine
Database Links
BindingDB Ligand 50336799
CAS Registry No. 145-63-1
ChEBI CHEBI:45906
ChEMBL Ligand CHEMBL265502
DrugBank Ligand DB04786
PharmGKB Drug PA10292
PubChem CID 5361
RCSB PDB Ligand SVR
Search Google for chemical match using the InChIKey FIAFUQMPZJWCLV-UHFFFAOYSA-N
Search Google for chemicals with the same backbone FIAFUQMPZJWCLV
Search PubMed clinical trials suramin sodium
Search PubMed titles suramin sodium
Search PubMed titles/abstracts suramin sodium
Wikipedia Suramin
Comments
Results of a search of the US drugs.com website records that "suramin is a known pharmaceutical ingredient" but no further details of its US approval status are available. Individual national agencies may have granted marketing approval for this drug.

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