G PROTEIN-COUPLED RECEPTORS
CLASS A
Class B | Class C | Frizzled class | Other 7TM proteins
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| 5-Hydroxytryptamine receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| 5-Hydroxytryptamine receptors | 5-hydroxytryptamine | 5-HT1A |
HTR1A |
Htr1a |
Htr1a |
|
| 5-Hydroxytryptamine receptors | 5-hydroxytryptamine | 5-HT1B |
HTR1B |
Htr1b |
Htr1b |
|
| 5-Hydroxytryptamine receptors | 5-hydroxytryptamine | 5-HT1D |
HTR1D |
Htr1d |
Htr1d |
|
| 5-Hydroxytryptamine receptors | 5-hydroxytryptamine | 5-ht1e |
HTR1E |
|||
| 5-Hydroxytryptamine receptors | 5-hydroxytryptamine | 5-HT1F |
HTR1F |
Htr1f |
Htr1f |
|
| 5-Hydroxytryptamine receptors | 5-hydroxytryptamine | 5-HT2A |
HTR2A |
Htr2a |
Htr2a |
|
| 5-Hydroxytryptamine receptors | 5-hydroxytryptamine | 5-HT2B |
HTR2B |
Htr2b |
Htr2b |
|
| 5-Hydroxytryptamine receptors | 5-hydroxytryptamine | 5-HT2C |
HTR2C |
Htr2c |
Htr2c |
|
| 5-Hydroxytryptamine receptors | 5-hydroxytryptamine | 5-HT4 |
HTR4 |
Htr4 |
Htr4 |
|
| 5-Hydroxytryptamine receptors | 5-hydroxytryptamine | 5-ht5a |
HTR5A |
Htr5a |
Htr5a |
|
| 5-Hydroxytryptamine receptors | 5-hydroxytryptamine | 5-ht5b |
HTR5BP |
Htr5b |
Htr5b |
|
| 5-Hydroxytryptamine receptors | 5-hydroxytryptamine | 5-HT6 |
HTR6 |
Htr6 |
Htr6 |
|
| 5-Hydroxytryptamine receptors | 5-hydroxytryptamine | 5-HT7 |
HTR7 |
Htr7 |
Htr7 |
|
| Acetylcholine receptors (muscarinic) | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Acetylcholine receptors (muscarinic) | acetylcholine | M1 |
CHRM1 |
Chrm1 |
Chrm1 |
|
| Acetylcholine receptors (muscarinic) | acetylcholine | M2 |
CHRM2 |
Chrm2 |
Chrm2 |
|
| Acetylcholine receptors (muscarinic) | acetylcholine | M3 |
CHRM3 |
Chrm3 |
Chrm3 |
|
| Acetylcholine receptors (muscarinic) | acetylcholine | M4 |
CHRM4 |
Chrm4 |
Chrm4 |
|
| Acetylcholine receptors (muscarinic) | acetylcholine | M5 |
CHRM5 |
Chrm5 |
Chrm5 |
|
| Adenosine receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Adenosine receptors | adenosine | A1 |
ADORA1 |
Adora1 |
Adora1 |
|
| Adenosine receptors | adenosine | A2A |
ADORA2A |
Adora2a |
Adora2a |
|
| Adenosine receptors | adenosine | A2B |
ADORA2B |
Adora2b |
Adora2b |
|
| Adenosine receptors | adenosine | A3 |
ADORA3 |
Adora3 |
Adora3 |
|
| Adrenoceptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Adrenoceptors | noradrenaline | α1A-adrenoceptor |
ADRA1A |
Adra1a |
Adra1a |
|
| Adrenoceptors | adrenaline | α1B-adrenoceptor |
ADRA1B |
Adra1b |
Adra1b |
|
| Adrenoceptors | adrenaline | α1D-adrenoceptor |
ADRA1D |
Adra1d |
Adra1d |
|
| Adrenoceptors | adrenaline | α2A-adrenoceptor |
ADRA2A |
Adra2a |
Adra2a |
|
| Adrenoceptors | adrenaline | α2B-adrenoceptor |
ADRA2B |
Adra2b |
Adra2b |
|
| Adrenoceptors | adrenaline | α2C-adrenoceptor |
ADRA2C |
Adra2c |
Adra2c |
|
| Adrenoceptors | noradrenaline | β1-adrenoceptor |
ADRB1 |
Adrb1 |
Adrb1 |
|
| Adrenoceptors | adrenaline | β2-adrenoceptor |
ADRB2 |
Adrb2 |
Adrb2 |
|
| Adrenoceptors | adrenaline | β3-adrenoceptor |
ADRB3 |
Adrb3 |
Adrb3 |
|
| Anaphylatoxin receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Anaphylatoxin receptors | anaphylatoxin C3a | C3a receptor |
C3AR1 |
C3ar1 |
C3ar1 |
|
| Anaphylatoxin receptors | anaphylatoxin C5a | C5a receptor |
C5AR1 |
C5ar1 |
C5ar1 |
|
| Anaphylatoxin receptors | anaphylatoxin C5a, C5a des Arg74 | C5L2 |
GPR77 |
Gpr77 |
Gpr77 |
|
| Angiotensin receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Angiotensin receptors | angiotensin | AT1 |
AGTR1 |
Agtr1b Agtr1a |
Agtr1b Agtr1a |
|
| Angiotensin receptors | angiotensin | AT2 |
AGTR2 |
Agtr2 |
Agtr2 |
|
| Apelin receptor | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Apelin receptor | apelin | apelin receptor |
APLNR |
Aplnr |
Aplnr |
|
| Bile acid receptor | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Bile acid receptor | bile acids | GPBA |
GPBAR1 |
Gpbar1 |
Gpbar1 |
|
| Bombesin receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Bombesin receptors | neuromedin B | BB1 |
NMBR |
Nmbr |
Nmbr |
|
| Bombesin receptors | gastrin-releasing peptide | BB2 |
GRPR |
Grpr |
Grpr |
|
| Bombesin receptors | BB3 |
BRS3 |
Brs3 |
Brs3 |
||
| Bradykinin receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Bradykinin receptors | bradykinin | B1 |
BDKRB1 |
Bdkrb1 |
Bdkrb1 |
|
| Bradykinin receptors | bradykinin | B2 |
BDKRB2 |
Bdkrb2 |
Bdkrb2 |
|
| Cannabinoid receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Cannabinoid receptors | cannabinoid | CB1 |
CNR1 |
Cnr1 |
Cnr1 |
|
| Cannabinoid receptors | cannabinoid | CB2 |
CNR2 |
Cnr2 |
Cnr2 |
|
| Chemokine receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Chemokine receptors | CCL3, CCL5, CCL7, CCL8, CCL13-16, CCL23 | CCR1 |
CCR1 |
Ccr1 |
Ccr1 |
|
| Chemokine receptors | CCL2, CCL7, CCL8, CCL13 | CCR2 |
CCR2 |
Ccr2 |
Ccr2 |
|
| Chemokine receptors | CCL11 (eotaxin); CCL5, CCL7, CCL8, CCL13, CCL15, CCL24, CCL26 | CCR3 |
CCR3 |
Ccr3 |
Ccr3 |
|
| Chemokine receptors | CCL17, CCL22 | CCR4 |
CCR4 |
Ccr4 |
Ccr4 |
|
| Chemokine receptors | CCL3, CCL4, CCL5, CCL8, CCL14 | CCR5 |
CCR5 |
Ccr5 |
Ccr5 |
|
| Chemokine receptors | CCL20 | CCR6 |
CCR6 |
Ccr6 |
Ccr6 |
|
| Chemokine receptors | CCL19, CCL21 | CCR7 |
CCR7 |
Ccr7 |
Ccr7 |
|
| Chemokine receptors | CCL1, CCL4, CCL17 | CCR8 |
CCR8 |
Ccr8 |
Ccr8 |
|
| Chemokine receptors | CCL25 | CCR9 |
CCR9 |
Ccr9 |
Ccr9 |
|
| Chemokine receptors | CCL26-28 | CCR10 |
CCR10 |
Ccr10 |
Ccr10 |
|
| Chemokine receptors | CXCL8 | CXCR1 |
CXCR1 |
Il8ra |
Cxcr1 |
|
| Chemokine receptors | CXCL1-3, CXCL5-8, macrophage derived lectin | CXCR2 |
CXCR2 |
Il8rb |
Cxcr2 |
macrophage derived lectin is a proposed ligand, single publication |
| Chemokine receptors | CXCL9-11 | CXCR3 |
CXCR3 |
Cxcr3 |
Cxcr3 |
|
| Chemokine receptors | CXCL12 | CXCR4 |
CXCR4 |
Cxcr4 |
Cxcr4 |
|
| Chemokine receptors | CXCL13 | CXCR5 |
CXCR5 |
Cxcr5 |
Cxcr5 |
|
| Chemokine receptors | CXCL16 | CXCR6 |
CXCR6 |
Cxcr6 |
Cxcr6 |
|
| Chemokine receptors | CXCR7 |
CXCR7 |
Cxcr7 |
Cxcr7 |
aka RDC1 | |
| Chemokine receptors | CX3CL1 | CX3CR1 |
CX3CR1 |
Cx3cr1 |
Cx3cr1 |
|
| Chemokine receptors | XCL1, XCL2 | XCR1 |
XCR1 |
Xcr1 |
Xcr1 |
|
| Cholecystokinin receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Cholecystokinin receptors | cholecystokinin | CCK1 |
CCKAR |
Cckar |
Cckar |
|
| Cholecystokinin receptors | cholecystokinin, gastrin | CCK2 |
CCKBR |
Cckbr |
Cckbr |
|
| Dopamine receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Dopamine receptors | dopamine | D1 |
DRD1 |
Drd1a |
Drd1a |
|
| Dopamine receptors | dopamine | D2 |
DRD2 |
Drd2 |
Drd2 |
|
| Dopamine receptors | dopamine | D3 |
DRD3 |
Drd3 |
Drd3 |
|
| Dopamine receptors | dopamine | D4 |
DRD4 |
Drd4 |
Drd4 |
|
| Dopamine receptors | dopamine | D5 |
DRD5 |
Drd5 |
Drd5 |
|
| Endothelin receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Endothelin receptors | endothelin 1, endothelin 2 | ETA |
EDNRA |
Ednra |
Ednra |
|
| Endothelin receptors | endothelins 1, 2 and 3 | ETB |
EDNRB |
Ednrb |
Ednrb |
|
| Estrogen (G protein coupled) receptor | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Estrogen (G protein coupled) receptor | GPER |
GPER |
Gper |
Gpr30 |
||
| Formylpeptide receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Formylpeptide receptors | FPR1 |
FPR1 |
Fpr1 |
Fpr1 |
||
| Formylpeptide receptors | FPR2/ALX |
FPR2 |
Fpr2 |
Fpr2 |
||
| Formylpeptide receptors | FPR3 |
FPR3 |
Fpr3 |
Fpr3 |
||
| Free fatty acid receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Free fatty acid receptors | long chain carboxylic acids | FFA1 |
FFAR1 |
Ffar1 |
Ffar1 |
|
| Free fatty acid receptors | FFA2 |
FFAR2 |
Ffar2 |
Ffar2 |
||
| Free fatty acid receptors | FFA3 |
FFAR3 |
Ffar3 |
Ffar3 |
||
| Free fatty acid receptors | GPR42 |
GPR42 |
Very closely related to GPR41. Might be pseudogene. | |||
| Galanin receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Galanin receptors | galanin | GAL1 |
GALR1 |
Galr1 |
Galr1 |
|
| Galanin receptors | galanin | GAL2 |
GALR2 |
Galr2 |
Galr2 |
|
| Galanin receptors | galanin | GAL3 |
GALR3 |
Galr3 |
Galr3 |
|
| Ghrelin receptor | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Ghrelin receptor | ghrelin | ghrelin receptor |
GHSR |
Ghsr |
Ghsr |
|
| Glycoprotein hormone receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Glycoprotein hormone receptors | follicle-stimulating hormone | FSH receptor |
FSHR |
Fshr |
Fshr |
|
| Glycoprotein hormone receptors | luteinizing hormone, chorionic gonadotropin | LH receptor |
LHCGR |
Lhcgr |
Lhcgr |
|
| Glycoprotein hormone receptors | thyroid-stimulating hormone | TSH receptor |
TSHR |
Tshr |
Tshr |
|
| Gonadotrophin-releasing hormone receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Gonadotrophin-releasing hormone receptors | gonadotrophin-releasing hormone | GnRH receptor |
GNRHR |
Gnrhr |
Gnrhr |
|
| Gonadotrophin-releasing hormone receptors | gonadotrophin-releasing hormone | GnRH2 receptor |
GNRHR2 |
probable transcribed pseudogene | ||
| Histamine receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Histamine receptors | histamine | H1 |
HRH1 |
Hrh1 |
Hrh1 |
|
| Histamine receptors | histamine | H2 |
HRH2 |
Hrh2 |
Hrh2 |
|
| Histamine receptors | histamine | H3 |
HRH3 |
Hrh3 |
Hrh3 |
|
| Histamine receptors | histamine | H4 |
HRH4 |
Hrh4 |
Hrh4 |
|
| Hydroxycarboxylic acid receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Hydroxycarboxylic acid receptors | lactate | HCA1 |
HCAR1 |
Gpr81 |
Gpr81 |
Proposed ligand, two publications |
| Hydroxycarboxylic acid receptors | nicotinic acid (high affinity) | HCA2 |
HCAR2 |
Gpr109a |
Niacr1 |
|
| Hydroxycarboxylic acid receptors | nicotinic acid (low affinity) | HCA3 |
HCAR3 |
|||
| Kisspeptin receptor | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Kisspeptin receptor | kisspeptin receptor |
KISS1R |
Kiss1r |
Kiss1r |
||
| Leukotriene receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Leukotriene receptors | leukotriene B4 | BLT1 |
LTB4R |
Ltb4r |
Ltb4r1 |
|
| Leukotriene receptors | leukotriene B4 | BLT2 |
LTB4R2 |
Ltb4r2 |
Ltb4r2 |
|
| Leukotriene receptors | leukotriene D4 | CysLT1 |
CYSLTR1 |
Cysltr1 |
Cysltr1 |
|
| Leukotriene receptors | leukotriene C4 | CysLT2 |
CYSLTR2 |
Cysltr2 |
Cysltr2 |
|
| Leukotriene receptors | 5-oxo-ETE | OXE |
OXER1 |
|||
| Leukotriene receptors | FPR2/ALX |
FPR2 |
Fpr2 |
Fpr2 |
||
| Lysophospholipid receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Lysophospholipid receptors | lysophosphatidic acid (LPA) | LPA1 |
LPAR1 |
Lpar1 |
Lpar1 |
|
| Lysophospholipid receptors | lysophosphatidic acid | LPA2 |
LPAR2 |
Lpar2 |
Lpar2 |
|
| Lysophospholipid receptors | lysophosphatidic acid | LPA3 |
LPAR3 |
Lpar3 |
Lpar3 |
|
| Lysophospholipid receptors | lysophosphatidic acid | LPA4 |
LPAR4 |
Lpar4 |
Lpar4 |
Proposed ligand, single publication |
| Lysophospholipid receptors | lysophosphatidic acid | LPA5 |
LPAR5 |
Lpar5 |
Lpar5 |
Proposed ligand, two publications |
| Lysophospholipid receptors | sphingosine 1-phosphate | S1P1 |
S1PR1 |
S1pr1 |
S1pr1 |
|
| Lysophospholipid receptors | sphingosine 1-phosphate | S1P2 |
S1PR2 |
S1pr2 |
S1pr2 |
|
| Lysophospholipid receptors | sphingosine 1-phosphate | S1P3 |
S1PR3 |
S1pr3 |
S1pr3 |
|
| Lysophospholipid receptors | sphingosine 1-phosphate | S1P4 |
S1PR4 |
S1pr4 |
S1pr4 |
|
| Lysophospholipid receptors | sphingosine 1-phosphate | S1P5 |
S1PR5 |
S1pr5 |
S1pr5 |
|
| Melanin-concentrating hormone receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Melanin-concentrating hormone receptors | MCH1 |
MCHR1 |
Mchr1 |
Mchr1 |
||
| Melanin-concentrating hormone receptors | MCH2 |
MCHR2 |
||||
| Melanocortin receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Melanocortin receptors | α-melanocyte stimulating hormone | MC1 |
MC1R |
Mc1r |
Mc1r |
|
| Melanocortin receptors | adrenocorticotropic hormone | MC2 |
MC2R |
Mc2r |
Mc2r |
|
| Melanocortin receptors | γ-melanocyte stimulating hormone | MC3 |
MC3R |
Mc3r |
Mc3r |
|
| Melanocortin receptors | β-melanocyte stimulating hormone | MC4 |
MC4R |
Mc4r |
Mc4r |
|
| Melanocortin receptors | α-melanocyte stimulating hormone | MC5 |
MC5R |
Mc5r |
Mc5r |
|
| Melatonin receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Melatonin receptors | melatonin | MT1 |
MTNR1A |
Mtnr1a |
Mtnr1a |
|
| Melatonin receptors | melatonin | MT2 |
MTNR1B |
Mtnr1b |
Mtnr1b |
|
| Motilin receptor | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Motilin receptor | motilin | motilin receptor |
MLNR |
aka GPR38 | ||
| Neuromedin U receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Neuromedin U receptors | neuromedin U | NMU1 |
NMUR1 |
Nmur1 |
Nmur1 |
|
| Neuromedin U receptors | neuromedin U | NMU2 |
NMUR2 |
Nmur2 |
Nmur2 |
|
| Neuropeptide FF/neuropeptide AF receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Neuropeptide FF/neuropeptide AF receptors | NPFF1 |
NPFFR1 |
Npffr1 |
|||
| Neuropeptide FF/neuropeptide AF receptors | NPFF2 |
NPFFR2 |
Npffr2 |
Npffr2 |
||
| Neuropeptide S receptor | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Neuropeptide S receptor | NPS receptor |
NPSR1 |
Npsr1 |
Npsr1 |
||
| Neuropeptide W/neuropeptide B receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Neuropeptide W/neuropeptide B receptors | NPBW1 |
NPBWR1 |
Npbwr1 |
Npbwr1 |
||
| Neuropeptide W/neuropeptide B receptors | NPBW2 |
NPBWR2 |
||||
| Neuropeptide Y receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Neuropeptide Y receptors | neuropeptide Y | Y1 |
NPY1R |
Npy1r |
Npy1r |
|
| Neuropeptide Y receptors | neuropeptide Y | Y2 |
NPY2R |
Npy2r |
Npy2r |
|
| Neuropeptide Y receptors | pancreatic polypeptide | Y4 |
PPYR1 |
Ppyr1 |
Ppyr1 |
|
| Neuropeptide Y receptors | neuropeptide Y | Y5 |
NPY5R |
Npy5r |
Npy5r |
|
| Neuropeptide Y receptors | y6 |
NPY6R |
Npy6r |
|||
| Neurotensin receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Neurotensin receptors | neurotensin | NTS1 |
NTSR1 |
Ntsr1 |
Ntsr1 |
|
| Neurotensin receptors | neurotensin | NTS2 |
NTSR2 |
Ntsr2 |
Ntsr2 |
|
| Opioid receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Opioid receptors | β-endorphin | δ |
OPRD1 |
Oprd1 |
Oprd1 |
|
| Opioid receptors | dynorphin A | κ |
OPRK1 |
Oprk1 |
Oprk1 |
|
| Opioid receptors | β-endorphin | μ |
OPRM1 |
Oprm1 |
Oprm1 |
|
| Opioid receptors | nociceptin/orphanin FQ | NOP |
OPRL1 |
Oprl1 |
Oprl1 |
|
| Orexin receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Orexin receptors | orexin A, orexin B | OX1 |
HCRTR1 |
Hcrtr1 |
Hcrtr1 |
|
| Orexin receptors | orexin A, orexin B | OX2 |
HCRTR2 |
Hcrtr2 |
Hcrtr2 |
|
| P2Y receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| P2Y receptors | ADP | P2Y1 |
P2RY1 |
P2ry1 |
P2ry1 |
|
| P2Y receptors | UTP, ATP | P2Y2 |
P2RY2 |
P2ry2 |
P2ry2 |
|
| P2Y receptors | UTP | P2Y4 |
P2RY4 |
P2ry4 |
P2ry4 |
|
| P2Y receptors | UDP | P2Y6 |
P2RY6 |
P2ry6 |
P2ry6 |
|
| P2Y receptors | ATP | P2Y11 |
P2RY11 |
|||
| P2Y receptors | ADP | P2Y12 |
P2RY12 |
P2ry12 |
P2ry12 |
|
| P2Y receptors | ADP | P2Y13 |
P2RY13 |
P2ry13 |
P2ry13 |
|
| P2Y receptors | UDP-glucose | P2Y14 |
P2RY14 |
P2ry14 |
P2ry14 |
|
| Peptide P518 receptor | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Peptide P518 receptor | RF-amide P518 gene product | QRFP |
QRFPR |
Qrfpr |
Qrfpr |
|
| Platelet-activating factor receptor | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Platelet-activating factor receptor | platelet-activating factor | PAF receptor |
PTAFR |
Ptafr |
Ptafr |
|
| Prokineticin receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Prokineticin receptors | PKR1 |
PROKR1 |
Prokr1 |
Prokr1 |
||
| Prokineticin receptors | PKR2 |
PROKR2 |
Prokr2 |
Prokr2 |
||
| Prolactin-releasing peptide receptor | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Prolactin-releasing peptide receptor | PRRP receptor |
PRLHR |
Prlhr |
Prlhr |
||
| Prostanoid receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Prostanoid receptors | prostaglandin D2 | DP1 |
PTGDR |
Ptgdr |
Ptgdr |
|
| Prostanoid receptors | 11-dehydro-thromboxane B2 | DP2 |
PTGDR2 |
Gpr44 |
Gpr44 |
|
| Prostanoid receptors | prostaglandin E2 | EP1 |
PTGER1 |
Ptger1 |
Ptger1 |
|
| Prostanoid receptors | prostaglandin E2 | EP2 |
PTGER2 |
Ptger2 |
Ptger2 |
|
| Prostanoid receptors | prostaglandin E2 | EP3 |
PTGER3 |
Ptger3 |
Ptger3 |
|
| Prostanoid receptors | prostaglandin E2 | EP4 |
PTGER4 |
Ptger4 |
Ptger4 |
|
| Prostanoid receptors | prostaglandin F2a | FP |
PTGFR |
Ptgfr |
Ptgfr |
|
| Prostanoid receptors | prostacyclin | IP1 |
PTGIR |
Ptgir |
Ptgir |
|
| Prostanoid receptors | thromboxane A2 | TP |
TBXA2R |
Tbxa2r |
Tbxa2r |
|
| Protease-activated receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Protease-activated receptors | thrombin | PAR1 |
F2R |
F2r |
F2r |
|
| Protease-activated receptors | serine proteases | PAR2 |
F2RL1 |
F2rl1 |
F2rl1 |
|
| Protease-activated receptors | thrombin | PAR3 |
F2RL2 |
F2rl2 |
F2rl2 |
|
| Protease-activated receptors | serine proteases | PAR4 |
F2RL3 |
F2rl3 |
F2rl3 |
|
| Relaxin family peptide receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene name | Rat gene name | Mouse gene name | Comment |
| Relaxin family peptide receptors | RXFP1 |
RXFP1 |
Rxfp1 |
Rxfp1 |
||
| Relaxin family peptide receptors | RXFP2 |
RXFP2 |
Rxfp2 |
Rxfp2 |
||
| Relaxin family peptide receptors | RXFP3 |
RXFP3 |
Rxfp3 |
Rxfp3 |
||
| Relaxin family peptide receptors | ||||||